How Do You Spell CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR?

Pronunciation: [sˈɪstɪk fɪbɹˈə͡ʊsɪs tɹansmˈɛmbɹe͡ɪn kəndˈʌktəns ɹˈɛɡjuːlˌe͡ɪtə] (IPA)

Cystic Fibrosis Transmembrane Conductance Regulator is a mouthful, but its spelling can be explained through IPA phonetic transcription. The first word, "cystic," is spelled with a soft "s" sound, like "siss-tick." "Fibrosis" is pronounced with a hard "f" sound, like "fye-broh-siss." "Transmembrane" is pronounced with the stress on the first syllable, like "trans-mem-brain." "Conductance" also has stress on the first syllable, and is pronounced "con-duck-tance." Finally, "Regulator" is spelled like it sounds, with stress on the second syllable, like "reg-yoo-lay-tor."

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Meaning and Definition

  1. The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a protein that plays a crucial role in maintaining the balance of ions, particularly chloride ions, in cells lining the airways, digestive system, sweat glands, and reproductive system. It is encoded by the CFTR gene found on chromosome 7.

    The CFTR protein functions as a gated channel located in the cell membrane, allowing the controlled flow of ions across the cellular barrier. Its primary job is to transport chloride ions out of cells, thereby regulating the movement of water and salt in and out of the cells. This process is vital for maintaining normal secretions, such as mucus, in various organs.

    Mutations in the CFTR gene lead to the development of cystic fibrosis (CF), a genetic disorder characterized by the production of thick, sticky mucus that clogs the airways, digestive tract, and other organs. CFTR mutations can disrupt the proper function of the CFTR protein, resulting in reduced chloride transport and impaired fluid balance in the affected organs.

    Suboptimal CFTR protein activity can lead to the accumulation of thick mucus in the airways, impairing lung function and increasing the risk of respiratory infections. In the digestive system, faulty CFTR protein can hinder the normal transport of digestive enzymes, leading to malabsorption of nutrients. Sweat glands can also be affected, resulting in excessively salty sweat.

    The understanding of CFTR and its role in the pathogenesis of cystic fibrosis has provided valuable insights into the development of targeted therapies aimed at restoring CFTR function or improving its activity. These therapies, known as CFTR modulators, have significantly improved the outlook for individuals with CF, offering the potential to address the underlying cause of the disease rather than just managing its symptoms

Common Misspellings for CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

  • xystic fibrosis transmembrane conductance regulator
  • vystic fibrosis transmembrane conductance regulator
  • fystic fibrosis transmembrane conductance regulator
  • dystic fibrosis transmembrane conductance regulator
  • ctstic fibrosis transmembrane conductance regulator
  • cgstic fibrosis transmembrane conductance regulator
  • chstic fibrosis transmembrane conductance regulator
  • custic fibrosis transmembrane conductance regulator
  • c7stic fibrosis transmembrane conductance regulator
  • c6stic fibrosis transmembrane conductance regulator
  • cyatic fibrosis transmembrane conductance regulator
  • cyztic fibrosis transmembrane conductance regulator
  • cyxtic fibrosis transmembrane conductance regulator
  • cydtic fibrosis transmembrane conductance regulator
  • cyetic fibrosis transmembrane conductance regulator
  • cywtic fibrosis transmembrane conductance regulator
  • cysric fibrosis transmembrane conductance regulator
  • cysfic fibrosis transmembrane conductance regulator
  • cysgic fibrosis transmembrane conductance regulator
  • cysyic fibrosis transmembrane conductance regulator

Plural form of CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR is CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATO

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