CURARE LIKE AGENTS Meaning and
Definition
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Curare Like Agents refer to a group of synthetic substances or drugs that possess similar properties and characteristics to curare, a naturally occurring poison. Curare is a toxic plant extract traditionally used by indigenous populations in South America for hunting and warfare purposes due to its ability to paralyze the muscles of prey and enemies. The term "curare like agents" is used to describe any artificial analogs or derivatives of curare, which have been chemically synthesized in laboratories for various medical and pharmaceutical applications.
These agents share the same pharmacological action as curare, which is the prevention of nerve impulses transmission to the muscles, resulting in temporary paralysis. By blocking the receptors that normally bind to the neurotransmitter acetylcholine, curare like agents induce muscular relaxation, which can be particularly useful during surgical interventions to facilitate muscle relaxation and immobilization.
Although curare like agents are structurally different from the natural curare, they possess similar therapeutic effects. They are commonly used as adjuncts in anesthesia to induce muscle relaxation during surgeries, including endotracheal intubation and laparoscopic procedures. Additionally, curare like agents have applications in the treatment of other medical conditions, such as muscle spasms, movement disorders, and certain neuromuscular diseases.
It is important to note that curare like agents should only be administered by trained medical professionals due to their potent muscle-paralyzing effects. Incorrect use or dosage can lead to respiratory paralysis and other serious complications.
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