How Do You Spell COMPLEMENTARY SEQUENCE?

Pronunciation: [kˌɒmplɪmˈɛntəɹi sˈiːkwəns] (IPA)

The spelling of "complementary sequence" is phonetically transcribed as /kɑmˈpləmənˌtɛri ˈsinkwəns/. The first syllable of "complementary" is pronounced with the "ah" sound as in "father" followed by a "m" sound. The word "sequence" has four syllables, with an emphasis in the second syllable pronounced as "kwens." Overall, the word is spelled the way it sounds, with each syllable enunciated clearly, making it easy to understand and pronounce.

COMPLEMENTARY SEQUENCE Meaning and Definition

1. A complementary sequence, in the context of molecular biology, refers to a sequence of DNA or RNA molecules that possesses a complementary base pairing to another nucleic acid sequence. This means that the nucleotide bases in one sequence are able to pair with their respective complementary bases in the other sequence, thereby forming stable base-pair interactions through hydrogen bonding.

   In DNA, the four nucleotide bases are adenine (A), thymine (T), cytosine (C), and guanine (G). According to the base pairing rule, A forms a hydrogen bond with T, while C forms a hydrogen bond with G. Therefore, a complementary sequence to a DNA sequence would have the opposite base pairing arrangement. For instance, if a DNA sequence has the base sequence ATCG, its complementary sequence would be TAGC. The two sequences can bind and form a double-stranded DNA molecule through hydrogen bonding between their respective complementary bases.

   Similarly, in RNA, uracil (U) replaces thymine (T) as one of the nucleotide bases. Thus, the base pairing rule in RNA is A-U and C-G. Hence, the complementary sequence for an RNA sequence would be formed by replacing each base with its respective complement.

   The concept of complementary sequences is fundamental to various molecular biology techniques, such as DNA hybridization, PCR (polymerase chain reaction), and gene cloning. It enables the selective binding and recognition of specific nucleic acid sequences, aiding in the analysis and manipulation of genetic information for research and clinical purposes.

Common Misspellings for COMPLEMENTARY SEQUENCE

• xomplementary sequence
• vomplementary sequence
• fomplementary sequence
• domplementary sequence
• cimplementary sequence
• ckmplementary sequence
• clmplementary sequence
• cpmplementary sequence
• c0mplementary sequence
• c9mplementary sequence
• conplementary sequence
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• complwmentary sequence

Etymology of COMPLEMENTARY SEQUENCE

The word "complementary sequence" in molecular biology refers to a sequence of nucleotides that are capable of forming base pairs with another specific sequence. The etymology of this term can be understood by examining the individual components:

1. Complementary: The term "complementary" comes from the Latin word "complementum", which means "that which completes or perfects". In the context of molecular biology, complementary refers to two sequences that fit together perfectly due to their specific base-pairing properties.

2. Sequence: The word "sequence" derives from the Latin word "sequi", which means "to follow" or "to order". In molecular biology, a sequence refers to the specific arrangement or order of nucleotides in a DNA or RNA molecule.

Plural form of COMPLEMENTARY SEQUENCE is COMPLEMENTARY SEQUENCES