Pronunciation: [kˈɒlt͡ʃɪsˌɪnə] (IPA) 
The word "colchicina" is spelled with the letter "c" followed by "o," "l," "c," "h," "i," "c," "i," "n," and "a." In IPA phonetic transcription, it is spelled as /kɒlˈtʃɪsɪnə/. The "ch" in "colchicina" is pronounced with a /tʃ/ sound. The stress in the word is on the second syllable (/ˈtʃɪsɪnə/). This word refers to a medication used to treat conditions such as gout and familial Mediterranean fever.
Colchicina is a noun that refers to a medication derived from the autumn crocus plant, colloquially known as the meadow saffron. It is commonly used to treat and manage gout, a form of arthritis caused by the deposition of uric acid crystals in the joints. The active ingredient in colchicina is colchicine, a natural compound found in the seed-like corms of the crocus plant.
Colchicina works by inhibiting the production and activity of certain enzymes, reducing the body's response to uric acid crystals and alleviating the inflammation and pain associated with gout. It is often prescribed for acute gout attacks and can also be used to prevent future episodes when taken regularly.
Besides its use in treating gout, colchicina may also be utilized in the management of other conditions, such as familial Mediterranean fever, a genetic disorder causing recurrent fevers and inflammation. Its anti-inflammatory properties make it effective in reducing the frequency and severity of symptoms associated with this condition.
When administered, colchicina is typically taken orally and may be available in various forms, including tablets and capsules. It is important to follow the prescribed dosage and duration of treatment, as colchicina should not be used without medical supervision due to potentially serious side effects, such as gastrointestinal upset and damage, low white blood cell count, and muscle weakness.
In summary, colchicina is a medication derived from the autumn crocus plant, commonly used in the treatment of gout and other inflammatory conditions. Its active ingredient, colchicine, helps reduce inflammation by inhibiting certain enzymes and is typically taken orally under medical supervision.
Colchicine, C22H25NO6, an alkaloid, obtained from colchicum, occurring in the form of a pale yellow crystalline powder or scales, employed in gout in doses of gr. 1/160-1/160 (0.0004-0.0006).
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "colchicina" can be traced back to its Latin origin, specifically from the Latin word "Colchicum". "Colchicum" refers to a genus of flowering plants that belong to the family Colchicaceae. These plants are commonly known as autumn crocus or meadow saffron. The name "Colchicum" itself is derived from the Greek word "Kolkhikon", which means "from Colchis". Colchis was an ancient region located in what is now present-day Georgia, near the eastern coast of the Black Sea. The word "colchicina" is the Spanish or Italian adaptation of "Colchicum", referring to a medication derived from these plants and primarily used to treat gout and other conditions.
