CHYMOTRYPSINOGEN Meaning and
Definition
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Chymotrypsinogen is a noun referring to an inactive precursor enzyme that is secreted by the pancreas and is a precursor of the digestive enzyme chymotrypsin. It is a zymogen, meaning it exists in an inactive form that requires activation to become functional.
Chymotrypsinogen belongs to the serine protease family and plays a vital role in the breakdown of proteins during digestion. It is synthesized in the acinar cells of the pancreas and then released into the small intestine.
The release of chymotrypsinogen is regulated by hormones, particularly cholecystokinin, which is secreted in response to the presence of food in the gastrointestinal tract. Upon activation, chymotrypsinogen is converted into chymotrypsin, an enzyme that helps in the hydrolysis of peptide bonds within proteins, specifically those adjacent to aromatic amino acids such as phenylalanine, tyrosine, and tryptophan.
The activation of chymotrypsinogen into chymotrypsin is facilitated by another enzyme called trypsin, which cleaves a specific peptide segment from chymotrypsinogen, resulting in the exposing of the active site of chymotrypsin. This activation mechanism prevents self-digestion of the pancreas by ensuring that chymotrypsinogen remains in its inactive form until it reaches the small intestine.
Overall, chymotrypsinogen is an essential precursor enzyme that undergoes activation to become chymotrypsin, enabling the hydrolysis of proteins during the process of digestion.
Common Misspellings for CHYMOTRYPSINOGEN
- xhymotrypsinogen
- vhymotrypsinogen
- fhymotrypsinogen
- dhymotrypsinogen
- cgymotrypsinogen
- cbymotrypsinogen
- cnymotrypsinogen
- cjymotrypsinogen
- cuymotrypsinogen
- cyymotrypsinogen
- chtmotrypsinogen
- chgmotrypsinogen
- chhmotrypsinogen
- chumotrypsinogen
- ch7motrypsinogen
- ch6motrypsinogen
- chynotrypsinogen
- chykotrypsinogen
- chyjotrypsinogen
- chymitrypsinogen
Etymology of CHYMOTRYPSINOGEN
The word "chymotrypsinogen" has a Greek etymology. It is derived from the Greek words "chymos" meaning "juice" or "pouring out" and "trysis" meaning "rubbing" or "friction". The ending "-gen" indicates that chymotrypsinogen is a precursor or inactive form of the enzyme chymotrypsin.
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