How Do You Spell CHUGAEV ELIMINATION?

Pronunciation: [t͡ʃˈuːɡiːv ɪlˌɪmɪnˈe͡ɪʃən] (IPA)

The Chugaev elimination is a chemical reaction used in organic synthesis. The word "Chugaev" is pronounced /tʃʊˈɡaɪɛv/ and is spelled as "ch-u-g-a-e-v". The IPA phonetic transcription explains that the "ch" sound is pronounced as in "church". The "u" sound is pronounced as in "put" and the "g" sounds as in "go". The "a" sound is pronounced as in "father" and the "e" sound is pronounced as in "bed". Finally, the "v" is pronounced as in "vet". Knowing the correct spelling and pronunciation of this word is essential for students and professionals in the field of organic chemistry.

CHUGAEV ELIMINATION Meaning and Definition

1. Chugaev elimination refers to a chemical reaction that involves the conversion of an organic halide compound, particularly alkyl halides, into corresponding alkenes or conjugated systems. This reaction is named after its discoverer, Russian chemist Aleksandr Y. Chugaev.

   The Chugaev elimination is typically carried out by heating an alkyl halide with an alcoholic solution of sodium ethoxide (NaOEt) or sodium methoxide (NaOMe) under reflux conditions. During this reaction, the halogen atom in the alkyl halide is replaced by the ethoxide or methoxide ion, resulting in the production of an alkene or a conjugated system.

   The reaction mechanism of Chugaev elimination involves the formation of an alkoxide ion through the nucleophilic attack of ethoxide or methoxide on the alkyl halide. This alkoxide ion then eliminates the halide anion, leading to the generation of the double bond or conjugated system. The overall reaction is considered an elimination reaction since a halogen atom is eliminated from the reactant.

   The Chugaev elimination is a useful synthetic method in organic chemistry for the synthesis of alkenes and conjugated systems. It offers a straightforward and efficient way to convert alkyl halides into unsaturated compounds with various applications in organic synthesis, including the production of pharmaceuticals, bioactive compounds, and natural products.

Etymology of CHUGAEV ELIMINATION

The term "Chugaev elimination" is named after the Russian chemist Aleksandr E. Chugaev. Born in 1873, Chugaev was a prominent organic chemist renowned for his contributions to the field of synthetic transformations. In 1923, he published a paper describing a specific elimination reaction involving thionyl chloride (SOCl2) and base, which came to be known as the "Chugaev elimination". The reaction is commonly used to convert alcohols to corresponding alkene compounds. The term "Chugaev elimination" emerged to honor Chugaev's significant contributions to the development of this reaction.