Chronic Active Hepatitis is a medical condition that affects the liver. It is spelled [krɑnɪk] [æktɪv] [hɛpəˈtaɪtɪs] in the International Phonetic Alphabet. The first syllable, [krɑnɪk], sounds like "krah-nik" and means that the condition is ongoing or long-lasting. The second syllable, [æktɪv], sounds like "ak-tiv" and describes the dynamic nature of the inflammation in the liver. Finally, [hɛpəˈtaɪtɪs], pronounced "hep-uh-tahy-tis", indicates that the condition specifically affects the liver, causing inflammation and liver damage if left untreated.
Chronic Active Hepatitis is a medical condition characterized by long-term inflammation of the liver. It is a progressive condition that leads to ongoing, persistent liver damage, often resulting in fibrosis, cirrhosis, and ultimately, liver failure if left untreated.
The term "chronic" refers to the prolonged duration of the condition, usually lasting for at least six months. "Active" indicates ongoing liver inflammation and damage, differentiating it from other forms of chronic hepatitis that may be relatively stable or inactive.
Chronic Active Hepatitis is primarily caused by viral infections, with hepatitis B, hepatitis C, and hepatitis D being the most common viral culprits. However, other factors such as autoimmune disorders, alcohol abuse, certain medications, or metabolic disorders may also contribute to its development.
Symptoms of Chronic Active Hepatitis can vary but often include fatigue, jaundice, abdominal pain, loss of appetite, and weight loss. As the condition progresses, individuals may also experience fluid accumulation in the abdomen, mental confusion, and even signs of liver failure.
Diagnosis typically involves medical history evaluation, physical examination, blood tests to determine liver function and the presence of viral markers, imaging studies, and liver biopsy to assess the degree of liver damage.
Treatment aims at managing symptoms, controlling liver inflammation, preventing disease progression, and ultimately, preserving liver function. Depending on the underlying cause, treatment options may include antiviral medications, immune system suppressants, lifestyle modifications, and regular medical monitoring.
In summary, Chronic Active Hepatitis is a long-term inflammatory condition of the liver that can lead to severe liver damage if not properly managed.