Chronic Active Hepatitis refers to a group of progressive inflammatory liver diseases characterized by ongoing inflammation, necrosis (cell death), and fibrosis (scar tissue formation) within the liver. It is a term used to describe a cluster of hepatitides (plural of hepatitis).
Hepatitis refers to inflammation of the liver, and chronic hepatitis indicates that the inflammation persists for an extended period, typically lasting for six months or more. Chronic Active Hepatitides, therefore, describes different types of hepatitis that have chronicity and an active inflammatory process occurring within the liver.
The term "active" denotes that there is ongoing inflammation and liver cell damage, which can potentially lead to the development of liver fibrosis, cirrhosis, and even liver failure if left untreated.
There are several forms of Chronic Active Hepatitis, including autoimmune hepatitis, viral hepatitis (such as hepatitis B, hepatitis C), and other less common forms caused by genetic or metabolic factors. Each form has its unique characteristics, causes, and progression patterns.
The management of Chronic Active Hepatitis typically involves the use of medications to suppress the immune system and reduce inflammation. In some cases, antiviral drugs may be prescribed to combat viral hepatitis. If the condition progresses to cirrhosis or liver failure, liver transplantation may be necessary.
Regular monitoring, including liver function tests and imaging studies, is crucial in the management of Chronic Active Hepatitis to assess disease progression and treatment efficacy.
