Chondrodysplasia is a medical condition marked by short stature and abnormal bone development. The pronunciation of chondrodysplasia can be tricky for many people as it contains a string of consonant sounds. The IPA phonetic transcription for this word is /kɒndrəʊdɪspleɪziə/. The first syllable of the word is "chon" where "ch" is pronounced as /k/. The following "dro" sounds like "draw" with an "o" sound, and "dys" is pronounced as /dɪs/. Lastly, the "plasia" part rhymes with "dysplasia" and is pronounced as /pleɪziə/.
Chondrodysplasia is a medical condition that affects skeletal development and growth, resulting in abnormal bone formation and shortened limbs. It is characterized by a type of dwarfism in which affected individuals exhibit shorter stature and disproportionate limb-to-body size ratios. The term "chondrodysplasia" is derived from the Greek words "chondros" meaning cartilage and "dys" meaning abnormal or impaired.
This genetic disorder typically manifests during infancy or childhood and may vary in severity among affected individuals. Chondrodysplasia can arise from various genetic mutations that disrupt the normal process of bone growth and cartilage formation. These mutations often affect the body's ability to produce or utilize a protein called collagen, which is necessary for the strength and flexibility of bones and cartilage.
Symptoms of chondrodysplasia include short stature, short and bowed limbs, abnormal joint development, and other skeletal deformities. Depending on the specific type and underlying genetic mutation, individuals with chondrodysplasia may also experience other complications such as joint pain, hearing loss, and spinal abnormalities.
Diagnosis of chondrodysplasia is usually made through physical examination, assessing the patient's growth patterns, and may involve radiographic imaging to evaluate bone and joint abnormalities. Treatment for chondrodysplasia aims to manage symptoms and may involve orthopedic interventions, physical therapy, or surgical procedures to correct skeletal deformities or alleviate associated complications. Genetic counseling is often recommended to affected individuals and their families to provide information about the inheritance pattern and discuss the likelihood of transmitting the condition to future generations.
Chondralloplasia.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "chondrodysplasia" originated from combining two Greek words: "chondros", meaning cartilage, and "dysplasia", meaning abnormal formation or growth.