CEPHALORIDINE Meaning and
Definition
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Cephaloridine is a noun that refers to a semi-synthetic antibiotic drug belonging to the cephalosporin class. It is derived from cephalosporin C and is primarily used for its potent bactericidal properties against a wide range of Gram-negative and some Gram-positive bacteria. First discovered in the 1960s, cephaloridine is an important therapeutic option in the treatment of various infections caused by susceptible microorganisms.
The mechanism of action of cephaloridine involves inhibiting the synthesis of bacterial cell walls by binding to and inhibiting the activity of penicillin-binding proteins (PBPs). This leads to impaired cell wall integrity and eventual bacterial lysis. As an antibiotic, cephaloridine is effective against commonly encountered pathogens such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and some strains of Streptococcus.
Cephaloridine is typically administered intravenously due to limited oral bioavailability. It is primarily used in hospitals for the treatment of severe infections, including urinary tract infections, respiratory tract infections, sepsis, skin and soft tissue infections, bone and joint infections, and certain types of meningitis. Moreover, as cephaloridine has a broad spectrum of activity, it can be utilized in cases where the causative bacteria are unknown or multiple organisms are involved.
Despite its efficacy, cephaloridine is associated with potential adverse effects and considerations. Common side effects include gastrointestinal disturbances, hypersensitivity reactions, and renal toxicity. It is important to note that cephaloridine is not effective against methicillin-resistant Staphylococcus aureus (MRSA) due to lack of activity against this particular bacteria strain.
Common Misspellings for CEPHALORIDINE
- xephaloridine
- vephaloridine
- fephaloridine
- dephaloridine
- cwphaloridine
- csphaloridine
- cdphaloridine
- crphaloridine
- c4phaloridine
- c3phaloridine
- ceohaloridine
- celhaloridine
- ce-haloridine
- ce0haloridine
- cepgaloridine
- cepbaloridine
- cepnaloridine
- cepjaloridine
- cepualoridine
Etymology of CEPHALORIDINE
The word "cephaloridine" is a compound word composed of "cephalo-" and "-ridine".
"Cephalo-" is derived from the Greek word "kephalḗ", meaning "head". It is commonly used as a prefix in scientific terms related to the head or brain. In this case, it refers to the beneficial effect of cephalosporin, the class of antibiotics to which cephaloridine belongs, on the central nervous system.
"-Ridine" is derived from "pyridine", which is an aromatic organic compound with a heterocyclic ring structure. Pyridine is commonly found in various compounds and pharmaceuticals. It is unclear why the specific term "-ridine" was selected for this context, but it is likely related to the chemical structure of cephaloridine.
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