Cephalosporanic acids are a group of antibiotics commonly used to treat bacterial infections. The word "cephalosporanic" consists of four syllables pronounced as /ˌkɛfəloʊspoʊˈrænɪk/. The first syllable "ceph" is pronounced like "kef," the second "a" is pronounced like "uh," and the third "lo" is pronounced like "low." The fourth syllable "spo" is pronounced like "spoh" and the last two "ra" and "nic" are pronounced like "ranik." Overall, the correct spelling of "cephalosporanic" can be difficult to remember due to its lengthy and complex structure.
Cephalosporanic acids are a class of chemical compounds that belong to the cephalosporin family of antibiotics. These compounds are characterized by possessing a beta-lactam ring structure, which is essential for their antibacterial activity. Cephalosporanic acids are derived from 7-aminocephalosporanic acid, which is the core structure of cephalosporin antibiotics.
Cephalosporanic acids exhibit broad-spectrum activity against a wide range of both Gram-positive and Gram-negative bacteria. They are particularly effective against certain strains that have developed resistance to penicillin antibiotics. This is due to differences in the structural modifications of the beta-lactam ring, which alter the affinity of these compounds for bacterial penicillin-binding proteins.
The cephalosporanic acids are typically classified into multiple generations, based on their antimicrobial spectrum and resistance to bacterial enzymes, called beta-lactamases. Each generation possesses different chemical modifications to enhance their effectiveness against specific bacterial species.
Cephalosporanic acids are primarily used in clinical settings for the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and certain sexually transmitted diseases. They can be administered orally or intravenously, depending on the severity of the infection.
While cephalosporanic acids are generally safe and well-tolerated, they can still cause adverse reactions in some individuals. Common side effects may include gastrointestinal disturbances, allergic reactions, and in rare cases, more serious effects such as severe hypersensitivity reactions or hematological abnormalities.
In summary, cephalosporanic acids are a diverse class of antibiotics derived from 7-aminocephalosporanic acid. They possess a broad spectrum of activity against bacteria and are
The word "Cephalosporanic Acids" is derived from two key components: "cephalosporin" and "acids".
The term "cephalosporin" originates from the genus name of a mold called Cephalosporium, which was discovered in 1945 by the Italian scientist Giuseppe Brotzu. This mold was found in a sewage outfall in Sardinia, Italy. Brotzu isolated and studied the mold, and later it was determined that the mold produced a compound with antibacterial properties, which was named cephalosporin.
The suffix "-an" signifies that Cephalosporanic Acids are related to or derived from cephalosporin. Meanwhile, "acids" refers to the chemical nature of these compounds, as they contain carboxylic acid functional groups.