CENTROMERIC SEQUENCE Meaning and
Definition
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A centromeric sequence refers to a specific DNA region found in eukaryotic chromosomes that plays a crucial role in cell division and chromosome segregation. It is typically localized at the centromere, a specialized region near the center of a chromosome.
The centromeric sequence is characterized by a specific DNA sequence that acts as an attachment site for proteins involved in chromosome organization and division. It is crucial for the proper alignment and separation of chromosomes during cell division, ensuring the accurate distribution of genetic material to daughter cells.
Centromeric sequences are highly conserved across species, maintaining their function and structure throughout evolution. Different organisms may have distinct types of centromeric sequences, such as alpha-satellite DNA in humans and yeast, or satellite DNA in plants.
The centromeric sequence plays a critical role in the establishment and maintenance of centromere structure and function. It not only mediates kinetochore formation, providing a physical link between the chromosomes and the microtubules of the spindle apparatus, but also helps prevent chromosomal rearrangements and instability.
Understanding the centromeric sequence and its associated proteins is of great importance in genetics and genomics research. Studying centromeric sequences can provide insights into chromosome behavior during cell division, chromosomal abnormalities, and genetic diseases associated with centromere dysfunction.
Common Misspellings for CENTROMERIC SEQUENCE
- xentromeric sequence
- ventromeric sequence
- fentromeric sequence
- dentromeric sequence
- cwntromeric sequence
- csntromeric sequence
- cdntromeric sequence
- crntromeric sequence
- c4ntromeric sequence
- c3ntromeric sequence
- cebtromeric sequence
- cemtromeric sequence
- cejtromeric sequence
- cehtromeric sequence
- cenrromeric sequence
- cenfromeric sequence
- cengromeric sequence
- cenyromeric sequence
- cen6romeric sequence
- cen5romeric sequence
Etymology of CENTROMERIC SEQUENCE
The term "centromeric sequence" is derived from the combination of two main components: "centromeric" and "sequence".
1. Centromeric: The word "centromeric" is derived from the root "centro-" meaning "center" and the combining form "-meric" meaning "part or segment". In biology, a centromere refers to the specialized region of a chromosome that plays a crucial role in cell division and chromosome segregation. It is located near the center of the chromosome and is essential in ensuring accurate distribution of chromosomes during cell division.
2. Sequence: The term "sequence" refers to a linear arrangement or order of nucleotides in DNA or RNA. In the context of genetics, it commonly refers to the specific order of nucleotide bases (adenine, thymine, cytosine, and guanine) that make up a particular DNA or RNA molecule.
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