The spelling of the word "Carbonyl Cyanide meta Chlorophenyl Hydrazone" can be quite challenging due to its length and complex molecular structure. The IPA phonetic transcription can help explain the correct pronunciation, which is [kɑrbənɪl saɪənaɪd ˌmitə klɔːrəˈfɛnɪl haɪdrəzoʊn]. This drug is commonly used in research to study mitochondrial function and is often abbreviated as CCCP. Despite its intimidating spelling, CCCP plays a crucial role in the scientific community and has led to many breakthroughs in biology and medicine.
Carbonyl Cyanide meta Chlorophenyl Hydrazone (CCCP) is a chemical compound that belongs to the class of hydrazones. It is commonly used in scientific research as a mitochondrial uncoupler and oxidative phosphorylation inhibitor. CCCP is typically synthesized by the reaction of 3-chlorobenzaldehyde with chlorohydrazine hydrochloride in the presence of sodium acetate.
CCCP is a small organic molecule that acts as a protonophore, meaning it disrupts the transmembrane electrochemical potential gradient across the mitochondrial membrane by carrying protons across it. By doing so, CCCP uncouples the electron transport chain from ATP synthesis, leading to increased oxygen consumption without ATP production. This effect is often exploited in cellular or biochemical studies to evaluate mitochondrial function, cell death pathways, and membrane potential-related processes.
Furthermore, CCCP is known to have multiple research applications such as the investigation of cellular respiration and the functioning of mitochondria. It is also utilized as a tool in physiological studies to elucidate the role of mitochondrial membrane potential in various cellular pathways. CCCP has been extensively employed in studies related to apoptosis, mitochondrial dynamics, reactive oxygen species generation, and the evaluation of drug effects on mitochondria.
In summary, Carbonyl Cyanide meta Chlorophenyl Hydrazone is a compound primarily used to disrupt the mitochondrial transmembrane potential and interfere with mitochondrial function. Its wide range of applications in scientific research makes CCCP an essential chemical tool for studying and understanding various physiological and cellular processes involving mitochondria.