The spelling of "Cancer Genes" is straightforward. It begins with the consonant sound /k/ represented by the letter C, followed by the vowel sound /æ/ represented by the letter A. The word "Cancer" then continues with the nasal consonant /n/ and the vowel sound /s/ represented by the letter S. Finally, the word ends with the consonant sounds /dʒ/ represented by the letters GE and the nasal consonant /z/ represented by the letter S. This word refers to genes that are involved in the development and progression of cancer.
Cancer genes, also known as oncogenes or tumor suppressor genes, are specific genes that play a critical role in the development and progression of cancer. These genes control the cycle of cell growth and division, as well as regulate the repair of damaged DNA. However, when cancer genes undergo specific changes or mutations, they can lead to abnormal cell growth and the formation of tumors.
Oncogenes are cancer genes that promote cell proliferation and survival. When these genes become altered, they become overactive, causing cells to divide rapidly and form a tumor. Mutations in oncogenes can be acquired during a person's lifetime, typically as a result of exposure to certain risk factors, environmental factors, or through genetic inheritance.
Tumor suppressor genes, on the other hand, normally act to halt the growth of potentially cancerous cells. They regulate cell cycle checkpoints, DNA repair mechanisms, and promote programmed cell death, or apoptosis, in cells with severe damage. When these genes are altered, they lose their ability to control cell division, DNA repair, and cell death, making it easier for cancer to develop.
Understanding the role of cancer genes is crucial in diagnosing and treating cancer. This knowledge has allowed scientists to develop targeted therapies that specifically aim to inhibit the activity of specific cancer genes or repair their malfunctioning mechanisms, thus preventing or delaying the progression of cancer. Additionally, studying cancer genes has facilitated the identification of genetic markers that can help predict a person's susceptibility to certain types of cancer, enabling earlier detection and intervention strategies.
The word "cancer" originates from the Latin word "cancer" which means "crab". It was chosen to describe this disease due to the crab-like appearance of some tumors, with their irregular shape and extensions resembling crab legs.
The term "genes" comes from the Greek word "genos", meaning "origin" or "birth". In the context of genetics, it refers to the hereditary material that is passed on from one generation to another, carrying genetic information.
Therefore, "cancer genes" refers to the specific genes that are associated with the development and progression of cancer. These genes include oncogenes, which promote abnormal cell growth, and tumor suppressor genes, which normally regulate cell growth but can become mutated or inactive in cancer, allowing uncontrolled cell growth.