CACONITASE Meaning and
Definition
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Caconitase is an enzyme that plays a crucial role in the mitochondrial tricarboxylic acid (TCA) cycle, also known as the citric acid cycle or Krebs cycle. It functions as an iron-sulfur protein that catalyzes the reversible isomerization of citrate to isocitrate. This enzymatic reaction is a key step in the TCA cycle, which takes place in the mitochondria of eukaryotic cells.
The TCA cycle is a fundamental metabolic pathway that generates high-energy molecules (ATP, NADH, and FADH2) and supplies intermediates that are essential for other biosynthetic pathways. Caconitase helps maintain the balance of metabolic intermediates by converting citrate into isocitrate, which can then be further processed to provide energy via oxidative phosphorylation or to participate in other biochemical reactions.
The caconitase enzyme is highly sensitive to the presence of reactive oxygen species (ROS). In the presence of ROS, caconitase can become inactivated due to the oxidation of its iron-sulfur cluster. This sensitivity makes caconitase not only a vital component of the TCA cycle but also a marker for oxidative stress in cells.
In summary, caconitase is an iron-sulfur enzyme that catalyzes the conversion of citrate to isocitrate in the TCA cycle. Its activity is crucial for energy production and the generation of key metabolic intermediates.
Common Misspellings for CACONITASE
- xaconitase
- vaconitase
- faconitase
- daconitase
- czconitase
- csconitase
- cwconitase
- cqconitase
- caxonitase
- cavonitase
- cafonitase
- cadonitase
- cacinitase
- cacknitase
- caclnitase
- cacpnitase
- cac0nitase
- cac9nitase
- cacobitase
- cacomitase
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