C KI RAS GENE Meaning and
Definition
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The c Ki ras gene, also known as the KRAS gene, is a highly significant gene involved in cell growth regulation and differentiation. It is a member of the RAS gene family, which includes other related genes such as HRAS and NRAS. The c Ki ras gene acts as an oncogene and plays a crucial role in various cellular processes, including cell proliferation, survival, and differentiation. It is located on the short arm of chromosome 12 (12p12.1) in humans.
The c Ki ras gene encodes a protein known as Kirsten rat sarcoma viral oncogene homolog, abbreviated as KRAS. This protein is a small GTPase that acts as a molecular switch, controlling the transmission of signals from the cell surface to the nucleus. Activation of the KRAS protein triggers a series of downstream signaling pathways, leading to cell proliferation and survival.
Mutations in the c Ki ras gene are commonly found in various human cancers, particularly in pancreatic, colorectal, and lung cancers. These mutations result in the constitutive activation of the KRAS protein, causing uncontrolled cell growth and proliferation. As a result, such cancers with c Ki ras gene mutations are often associated with poor prognosis and resistance to certain targeted therapies.
Understanding the function and mutations of the c Ki ras gene is crucial for developing targeted therapies and personalized medicine approaches for the treatment of cancer.
Common Misspellings for C KI RAS GENE
- x ki ras gene
- v ki ras gene
- f ki ras gene
- d ki ras gene
- c ji ras gene
- c mi ras gene
- c li ras gene
- c oi ras gene
- c ii ras gene
- c ku ras gene
- c k9 ras gene
- c k8 ras gene
- c ki eas gene
- c ki das gene
- c ki fas gene
- c ki tas gene
- c ki 5as gene
- c ki 4as gene
- c ki rzs gene
- c ki rss gene
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