C FMS GENE Meaning and
Definition
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The c fms gene, also known as the colony-stimulating factor 1 receptor (CSF1R) gene, is a gene that codes for a protein involved in immune system regulation and cell differentiation. It is located on chromosome 5 in humans. The c fms gene is responsible for producing a receptor protein called CSF1R, which is primarily found on the surface of cells of the immune system, such as macrophages and monocytes.
This gene plays a crucial role in the activation and differentiation of immune cells. It acts as a receptor for colony-stimulating factor 1 (CSF1), a molecule that stimulates the growth and differentiation of cells involved in the immune response, particularly macrophages. Once CSF1 binds to the CSF1R receptor, it triggers a signaling cascade that leads to the activation and maturation of immune cells.
Mutations or alterations in the c fms gene can result in dysregulation of the immune system and have been implicated in various diseases. For example, overactivity or increased expression of CSF1R has been associated with certain types of cancer, including leukemia and breast cancer. Conversely, mutations that impair the function of CSF1R can lead to a rare genetic disorder called hereditary diffuse leukoencephalopathy with spheroids (HDLS).
Understanding the function and regulation of the c fms gene and its protein product provides valuable insights into the mechanisms of immune system regulation and can potentially help in the development of targeted therapies for immune-related diseases and cancers.
Common Misspellings for C FMS GENE
- x fms gene
- v fms gene
- f fms gene
- d fms gene
- c dms gene
- c cms gene
- c vms gene
- c gms gene
- c tms gene
- c rms gene
- c fns gene
- c fks gene
- c fjs gene
- c fma gene
- c fmz gene
- c fmx gene
- c fmd gene
- c fme gene
- c fmw gene
- c fms fene
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