BIOTINYLATIONS Meaning and
Definition
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Biotinylations refer to the process of covalently attaching biotin molecules to specific molecules or structures. Biotin is a vitamin that plays a crucial role in various biological processes, especially in enzyme reactions. Biotinylations are commonly used in biochemical and molecular biology research to label proteins, nucleic acids, or other molecules for detection, purification, or visualization purposes.
During biotinylation, biotin molecules are attached to specific target molecules by forming a stable covalent bond. This attachment process can be achieved through various chemical reactions, such as amide formation or thiol-disulfide exchange. Biotin molecules are typically attached to specific functional groups present on the target molecule, such as primary amines, sulfhydryl groups, or carboxyl groups.
The addition of biotin molecules to the target molecule enables the subsequent use of avidin or streptavidin, which have a high affinity for biotin. This property allows for the easy detection or purification of the biotinylated molecules using labeled avidin or streptavidin conjugates, such as fluorescent dyes, enzymes, or magnetic beads.
Biotinylations find broad applications in various research fields, including protein analysis, immunoassays, protein purification, cell imaging, and drug delivery systems. They provide a versatile and highly specific method for labeling and manipulating molecules of interest, facilitating their visualization and characterization. Additionally, the strong binding affinity between biotin and avidin/streptavidin contributes to the sensitivity and accuracy of many assays and techniques used in biological research.
Common Misspellings for BIOTINYLATIONS
- viotinylations
- niotinylations
- hiotinylations
- giotinylations
- buotinylations
- bjotinylations
- bkotinylations
- bootinylations
- b9otinylations
- b8otinylations
- biitinylations
- biktinylations
- biltinylations
- biptinylations
- bi0tinylations
- bi9tinylations
- biorinylations
- biofinylations
- bioginylations
- bioyinylations
Etymology of BIOTINYLATIONS
The word "biotinylations" is derived from the noun "biotin" with the addition of the suffix "-ylations".
The term "biotin" originates from the German word "biotin", which was coined by the biochemist Paul Karrer in 1936. The name "biotin" was derived from the Greek word "biotos", meaning "sustenance" or "life".
The suffix "-ylations" is a combination of the suffix "-yl", which is used to denote a radical or a group derived from an alkane, and the suffix "-ation", which indicates an action, process, or result.
Therefore, "biotinylations" refers to the process of attaching or adding a biotin moiety or group to a molecule or substance.
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