Benign Recurrent Abducens Palsy of Childhood is a rare condition that affects the nerves of the eye, specifically the nerve that controls lateral eye movement or abduction. Its spelling in IPA phonetic transcription is /bɪˈnaɪn rɪˈkʌrənt əbˈdjuːsənz ˈpælsi əv ˈtʃaɪldhʊd/. The word "benign" means harmless, while "recurrent" means happening repeatedly. "Abducens" refers to the sixth cranial nerve, and "palsy" means paralysis or weakness. This condition typically affects children and usually resolves on its own without any long-term effects on vision.
Benign Recurrent Abducens Palsy of Childhood (BRAPC) is a medical condition characterized by recurrent episodes of temporary dysfunction of the abducens nerve, leading to the inability to fully or partially move the affected eye outward (abduction). This condition primarily affects children, usually between the ages of 2 and 10 years old.
The abducens nerve, also known as the sixth cranial nerve, controls the movement of the eye muscles responsible for outward eye movement. In BRAPC, the abducens nerve is intermittently affected, resulting in periodic paralysis or weakness of the eye muscle, causing a characteristic inward deviation of the affected eye (esotropia) and decreased ability to look sideways.
The episodes of abducens palsy in BRAPC are typically sudden in onset and may last for several hours to days before spontaneously resolving without any specific treatment. Between episodes, the affected eye's movement returns to normal, and the child remains symptom-free.
The exact cause of BRAPC is unknown, but it is believed to have a benign, self-limiting nature, meaning it does not lead to any significant long-term complications or progressive neurological damage. It is hypothesized that the condition may occur due to a developmental abnormality or dysfunction of the abducens nerve.
It is important to differentiate BRAPC from other more serious conditions that can cause recurrent eye muscle weakness, such as neurologic disorders or muscular diseases. A thorough examination of the eye movements and neurological evaluation is usually sufficient to make a diagnosis of BRAPC, and no specific treatment is required for this benign condition.