The word "basophile" refers to a type of white blood cell that is attracted to alkaline stains. Its spelling is derived from the Greek words "basis," meaning base, and "philein," meaning to love. The IPA phonetic transcription of "basophile" is /ˈbeɪsəˌfaɪl/. The first syllable "ba" is pronounced as "bay," the second syllable "so" is pronounced as "suh," and the suffix "-phile" is pronounced as "file," with the stress on the second syllable. This word is commonly used in medical texts and research literature.
A basophile is a specific type of white blood cell, also known as a basophil, that plays an important role in the immune system. Basophils are characterized by their large size and have granules in their cytoplasm that contain various chemicals, such as histamine and heparin. They are formed in the bone marrow and are released into the bloodstream, where they circulate throughout the body.
Functionally, basophils are involved in the body's allergic response and immune defense against parasitic infections. When an allergic reaction occurs, basophils are activated and release histamine, a chemical that causes dilation of blood vessels, increased permeability, and smooth muscle contraction. This results in the typical symptoms of allergy, such as itching, redness, and swelling.
Furthermore, basophils participate in the recruitment and activation of other immune cells. They can also release heparin, which acts as an anticoagulant, preventing blood clotting and allowing easier movement of immune cells to the site of infection.
In a healthy individual, basophils typically constitute a small percentage of the total white blood cell count. However, their levels may increase during allergic reactions, certain infections, or rare disorders. A high number of basophils in the blood, known as basophilia, may indicate an underlying medical condition that requires further investigation and diagnosis.
The word "basophile" is derived from two Greek roots: "basis", meaning "base" or "foundation", and "philos", meaning "loving" or "attraction". Therefore, the term "basophile" can be understood as "base-loving" or "attracted to the base". This etymology reflects the role of basophils, which are a type of white blood cell with granules containing basic dyes that stain blue-purple under a microscope.