ATROPISOMER Meaning and
Definition
-
Atropisomers are a specific type of stereoisomers that exist due to hindered rotation around a single covalent bond. The term "atropisomer" is derived from the prefix "atrop-" which means non-rotating or immobile. Atropisomers exhibit chirality and can exist as separate enantiomers or diastereomers.
These isomers are characterized by the presence of a chiral axis or hindered bond rotation that prevents interconversion between their enantiomers at room temperature. Consequently, atropisomers often have distinct physical, chemical, and biological properties, making their separation and study important in various scientific fields.
The most common type of atropisomer is found in compounds containing an aromatic system with bulky substituents. These substituents create steric hindrance that hinders the rotation around a particular bond, resulting in the atropisomeric behavior.
Atropisomers have found widespread use in various disciplines, particularly in medicinal chemistry, where they can influence the pharmacological properties of drugs. Understanding and manipulating atropisomers can lead to the development of more effective and selective pharmaceuticals.
Overall, atropisomers are stereoisomers that possess a hindered rotation around a bond, leading to the existence of distinct enantiomers or diastereomers. Their unique properties make them an essential area of study in chemistry, as they can have significant implications in drug design, materials science, and other fields.
Common Misspellings for ATROPISOMER
- ztropisomer
- stropisomer
- wtropisomer
- qtropisomer
- arropisomer
- afropisomer
- agropisomer
- ayropisomer
- a6ropisomer
- a5ropisomer
- ateopisomer
- atdopisomer
- atfopisomer
- attopisomer
- at5opisomer
- at4opisomer
- atripisomer
- atrkpisomer
- atrlpisomer
- atrppisomer
Etymology of ATROPISOMER
The word "atropisomer" is derived from two components: "atrop-" and "-isomer".
The root "atrop-" comes from the Greek word "atropos", which means "inflexible" or "unbending". In Greek mythology, Atropos was one of the three Moirai or Fates who controlled the thread of life and determined the moment of death. The term "atropos" reflects the idea of something that cannot be easily changed or altered.
The suffix "-isomer" is derived from the Greek word "isomerēs", which means "equal parts". In chemistry, an isomer is a compound that has the same molecular formula but different structural arrangements or spatial orientations.
Infographic
Add the infographic to your website:
