How Do You Spell ASPARTYLGLYCOSAMINE AMIDOHYDROLASE?

Pronunciation: [ɐspˌɑːtɪlɡlɪkˈɒsɐmˌiːn ɐmˈɪdə͡ʊˌa͡ɪdɹəlˌe͡ɪs] (IPA)

The spelling of the word "Aspartylglycosamine Amidohydrolase" is quite complex, with a total of 31 letters. The word is pronounced /æˌspɑrtilˌɡlaɪkoʊsəmiːn əˌmɪdoʊhaɪˈdroʊleɪs/ based on the International Phonetic Alphabet transcription. This compound word is made up of three parts: "Aspartyl", "glycosamine", and "amidohydrolase," each contributing to its meaning. The pronunciation of each syllable is important to ensure proper communication and understanding in scientific and medical contexts where the term is commonly used.

ASPARTYLGLYCOSAMINE AMIDOHYDROLASE Meaning and Definition

1. Aspartylglycosamine amidohydrolase, also known as AGA, is an enzyme that plays a significant role in various biological processes, specifically in the degradation of glycoproteins. This enzyme belongs to the class of hydrolases, which catalyze the hydrolysis of chemical bonds using water molecules.

   AGA acts on aspartylglycosamine, a derivative of glycoproteins, and facilitates the cleavage of the amide bond between the aspartate residue and the attached sugar chain. By breaking down the aspartylglycosamine, AGA helps in the recycling and turnover of glycoproteins in the body.

   The enzymatic activity of AGA is especially important in lysosomes, which are small organelles within cells responsible for digesting waste materials. AGA works in conjunction with other enzymes in the lysosome to break down glycoproteins into their constituent components, including amino acids and sugars. The resulting breakdown products can then be reused by the cell for various metabolic processes.

   Deficiencies in AGA activity have been linked to a rare genetic disorder called aspartylglycosaminuria. This condition leads to the accumulation of aspartylglycosamine in the lysosomes, causing the characteristic symptoms associated with the disorder, such as mental retardation, impaired motor skills, and abnormal facial features.

   In summary, aspartylglycosamine amidohydrolase is an enzyme responsible for the hydrolysis of aspartylglycosamine, leading to the degradation and recycling of glycoproteins. Its role in lysosomal function makes it a crucial player in maintaining cellular homeostasis and preventing the build-up of waste products.

Common Misspellings for ASPARTYLGLYCOSAMINE AMIDOHYDROLASE

• zspartylglycosamine amidohydrolase
• sspartylglycosamine amidohydrolase
• wspartylglycosamine amidohydrolase
• qspartylglycosamine amidohydrolase
• aapartylglycosamine amidohydrolase
• azpartylglycosamine amidohydrolase
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• adpartylglycosamine amidohydrolase
• aepartylglycosamine amidohydrolase
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• asoartylglycosamine amidohydrolase
• aslartylglycosamine amidohydrolase
• as-artylglycosamine amidohydrolase
• as0artylglycosamine amidohydrolase
• aspzrtylglycosamine amidohydrolase
• aspsrtylglycosamine amidohydrolase
• aspwrtylglycosamine amidohydrolase
• aspqrtylglycosamine amidohydrolase
• aspaetylglycosamine amidohydrolase
• aspadtylglycosamine amidohydrolase

Etymology of ASPARTYLGLYCOSAMINE AMIDOHYDROLASE

The word "Aspartylglycosaminease" is a scientific term, commonly referred to as AGA (the abbreviation for the enzyme). Let's break down the etymology of the word:

1. Aspartyl: This part of the word is derived from the amino acid "aspartic acid", which is one of the 20 standard amino acids that make up proteins. The term "aspartyl" indicates that this enzyme has an aspartic acid residue involved in its structure or function.

2. Glycosamine: This component of the word derives from "glucosamine", a naturally occurring compound that is an amino sugar. It is a constituent of many important biomolecules, such as chitin and glycosaminoglycans. The term "glycosamine" signifies that this enzyme is involved in the modification or breakdown of molecules containing glucosamine.