ASPARTATE KINASE Meaning and
Definition
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Aspartate kinase is an enzyme that plays a crucial role in the biosynthesis of an important amino acid called aspartate. It is a key regulatory enzyme in the metabolic pathway known as the aspartate family amino acid biosynthesis pathway. Aspartate kinase catalyzes the first step of this pathway, which involves the transfer of a phosphate group from ATP (adenosine triphosphate) to aspartate, resulting in the production of a molecule called β-aspartyl phosphate.
This enzyme is found in both prokaryotes and eukaryotes, and it is highly conserved across different species. Aspartate kinase exists in multiple isoforms, with each isoform being specific to a particular organism or cell type. These isoforms possess similar catalytic activities but may vary in their regulation and expression patterns.
The activity of aspartate kinase is tightly regulated in response to the cellular and environmental conditions. This regulation ensures that the production of aspartate is maintained at appropriate levels to meet the demands of the cell. The activity of aspartate kinase can be modulated by various factors, including the concentration of aspartate, the availability of ATP and other nucleotides, and the presence of allosteric effectors.
Aspartate kinase is an essential enzyme in many biological processes, such as protein synthesis, nucleic acid metabolism, and cellular respiration. Mutations or disruptions in the function of this enzyme can have significant consequences on cellular metabolism and contribute to various diseases and disorders. Therefore, understanding the structure, function, and regulation of aspartate kinase is critical in both basic research and the development of targeted therapies.
Common Misspellings for ASPARTATE KINASE
- zspartate kinase
- sspartate kinase
- wspartate kinase
- qspartate kinase
- aapartate kinase
- azpartate kinase
- axpartate kinase
- adpartate kinase
- aepartate kinase
- awpartate kinase
- asoartate kinase
- aslartate kinase
- as-artate kinase
- as0artate kinase
- aspzrtate kinase
- aspsrtate kinase
- aspwrtate kinase
- aspqrtate kinase
- aspaetate kinase
- aspadtate kinase
Etymology of ASPARTATE KINASE
The word "Aspartate" comes from the Latin word "asparagium", which means "stem of asparagus". It was named this way because asparagus was one of the first sources from which aspartate was identified. The word "Kinase" comes from the ancient Greek word "kinein", which means "to move". In biochemistry, a kinase is an enzyme that facilitates the transfer of phosphate groups from high-energy donor molecules to specific target molecules. Therefore, "Aspartate Kinase" refers to an enzyme that plays a role in the chemical reaction involving aspartate and the transfer of a phosphate group.
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