The word "apituitarism" refers to an underactive pituitary gland. The IPA phonetic transcription of this word is /ˌæpɪtɪtjʊəˈrɪz(ə)m/. The first syllable is pronounced as "ap-i," as in apple or after. The following two syllables "ti-tu" are pronounced with a short "i" sound, as in tick or fit, and a "u" sound pronounced as in put or push. The final syllable "ar-ism" is pronounced with the stress on the "a," as in car or bar, and a soft "s" sound.
Apituitarism refers to a medical condition characterized by the deficient or impaired secretion of hormones normally produced by the pituitary gland. The pituitary gland, located at the base of the brain, is often referred to as the "master gland" due to its vital role in regulating various physiological functions through hormone secretion.
The condition of apituitarism can arise as a result of structural damage or dysfunction of the pituitary gland itself, or due to a lack of hormone stimulation from the hypothalamus (a nearby brain region that controls hormone release). This can occur due to congenital abnormalities, genetic mutations, inflammatory or autoimmune diseases, tumors, radiation therapy, or traumatic brain injury.
Apituitarism commonly manifests as a deficiency in multiple hormones produced by the pituitary gland, such as growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, luteinizing hormone, follicle-stimulating hormone, prolactin, and antidiuretic hormone. Consequently, individuals with apituitarism may experience a range of symptoms depending on which hormones are affected, including growth retardation, weight gain, fatigue, sexual dysfunction, infertility, menstrual irregularities, low blood pressure, and water-electrolyte imbalances.
The diagnosis of apituitarism typically involves comprehensive medical history evaluation, physical examination, and hormonal blood tests. Treatment usually involves hormone replacement therapy to supplement the deficient hormones and manage the associated symptoms. Close monitoring and regular follow-ups are necessary to ensure appropriate dosing and to adjust the treatment regimen as needed.
A condition of total abeyance of functional activity in, or absence of, the pituitary body, or hypophysis cerebri; it results in cachexia hypophyseopriva.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "apituitarism" is derived from two components: "api-" and "tuitarism".
1. "Api-" is derived from "ap(i)-", a prefix borrowed from the Greek word "ápi-" meaning "away from" or "off". It is often used as a negative or privative prefix in medical terms, indicating a deficiency or absence of something.
2. "Tuitarism" is derived from "tuitar", which comes from "tuitary" or "pituitary". The word "pituitary" originates from the Latin term "pituitarius" meaning "phlegmatic" or "suffering from nasal mucus". This Latin term was derived from the Latin word "pituita" meaning "nasal mucus" or "phlegm".