How Do You Spell ANTIGLOBULIN?

Pronunciation: [ˌantɪɡlˈɒbjʊlˌɪn] (IPA)

The word "antiglobulin" is a mouthful to say, but it's a vital term in the medical field. The IPA phonetic transcription for "antiglobulin" is /æntiːɡləuːbjʊlɪn/. The first syllable, "anti," means "against," while "globulin" refers to a group of proteins found in blood plasma. An antiglobulin test is used to detect antibodies that attack red blood cells, a condition known as hemolytic anemia. Proper spelling and pronunciation of medical terms can make a big difference in understanding complex medical conditions.

ANTIGLOBULIN Meaning and Definition

1. Antiglobulin refers to a test or substance used in immunology and hematology aimed at specifically detecting the presence of antibodies or complement proteins that are bound to or coating the surface of red blood cells or other target cells. Also known as the Coombs test, antiglobulin is a diagnostic method primarily utilized to investigate various types of immune-mediated disorders and transfusion reactions.

   The term "antiglobulin" can also refer to the specific antibodies used in this test, known as polyclonal or monoclonal antiglobulin reagents. These reagents, typically derived from animals or produced in a laboratory, act as a binding agent and detect the binding of antibodies or complement proteins to the target cells. They are often labeled with fluorescent or enzymatic markers for easy visualization and quantification.

   The antiglobulin test involves mixing a patient's blood sample with the antiglobulin reagent, followed by careful observation for any visible clumping or agglutination of the red blood cells. If clumping occurs, it indicates the presence of antibodies or complement proteins on the surface of the cells, which can be indicative of autoimmune diseases, hemolytic anemias, or transfusion reactions.

   The antiglobulin test is an essential tool in clinical laboratories and blood banks for diagnosing and managing various conditions related to immune-mediated reactions. By detecting and identifying these antibodies or complement proteins, the test helps in guiding appropriate treatment options and ensures the safety and compatibility of blood transfusions.

Common Misspellings for ANTIGLOBULIN

• antiglobulina
• antiglobuline
• antiglobulinw
• antiglobulin
• Antiglobulin3
• andoglobulin
• zntiglobulin
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• anyiglobulin
• an6iglobulin
• an5iglobulin

Etymology of ANTIGLOBULIN

The word "antiglobulin" is derived from two main components: "anti-" and "globulin".

1. "Anti-" is a prefix in English derived from the Greek word "antí" (ἀντί), meaning "against" or "opposite". In scientific terminology, the prefix is used to indicate something that fights against or opposes a specific target.

2. "Globulin" refers to a group of proteins found in the blood plasma. It comes from the Latin word "globulus", which means "small sphere" or "little globe". The term "globulin" specifically refers to a type of protein that is soluble in water and found in the plasma.

Therefore, "antiglobulin" refers to a substance or technique that acts against or interacts with globulins.

Plural form of ANTIGLOBULIN is ANTIGLOBULINS