ANGIOSTROPHE Meaning and
Definition
-
Angiostrophe is a term primarily used in biology and medicine to refer to the process of blood vessels reorienting or redirecting in response to certain stimuli or conditions. Derived from the Greek words "angeion," meaning vessel, and "strophe," meaning a turning or direction, angiostrophe specifically describes the phenomenon of blood vessels changing their route or direction.
In the context of angiogenesis, the formation of new blood vessels, angiostrophe occurs when pre-existing blood vessels undergo remodeling or branching to meet the increasing oxygen and nutrient demands of tissues or in response to an injury. This reorientation may involve the growth of new blood vessels from existing ones, as well as the elongation and reorganization of the capillaries.
Angiostrophe plays a crucial role in numerous biological processes, such as development, wound healing, and the progression of certain diseases, including cancer. It is regulated by a variety of signaling molecules, such as growth factors and cytokines, which promote or inhibit blood vessel growth and remodeling.
Understanding angiostrophe is essential in the fields of medicine and research, as it provides insights into how blood vessels adapt and respond to physiological and pathological conditions. By studying angiostrophe, researchers aim to develop therapeutic strategies that can manipulate blood vessel growth and remodeling, potentially leading to treatments for diseases like cancer, diabetic retinopathy, and cardiovascular disorders.
Etymology of ANGIOSTROPHE
The term "angiostrophe" is formed by combining two Greek words: "angeion" meaning "vessel" or "container", and "strophe" meaning "turning" or "twisting". Thus, "angiostrophe" is composed of "angio-" referring to blood vessels, and "-strophe" indicating a turning or twisting motion. In biomedical terminology, "angiostrophe" typically refers to the elongation, growth, or branching of blood vessels.
