ANGIOSTOSIS Meaning and
Definition
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Angiostasis is a medical term that refers to the cessation or inhibition of the growth of new blood vessels, specifically in the context of angiogenesis, which is the physiological process of forming new blood vessels from pre-existing ones. The term "angiostasis" is derived from the Greek words "angeion" meaning "vessel," and "stasis" meaning "stoppage" or "inhibition."
Angiostasis is an important process in various clinical settings, as abnormal angiogenesis can contribute to the development and progression of numerous diseases, including cancer, diabetic retinopathy, and certain inflammatory conditions. By inhibiting the formation of new blood vessels, angiostasis can help suppress the blood supply to tumors, thus limiting their growth and preventing their spread to other tissues.
Various approaches can be used to induce angiostasis, such as the use of anti-angiogenic drugs, which are designed to inhibit specific molecular pathways involved in angiogenesis. These drugs can target specific growth factors or receptors, preventing the signaling required for blood vessel formation. Another approach involves the use of local therapies, such as laser photocoagulation or cryotherapy, which physically destroy abnormal blood vessels.
Overall, angiostasis is a critical concept in medical research and the development of therapies aimed at controlling pathological angiogenesis. Understanding the mechanisms underlying angiostasis and its manipulation may lead to significant advances in the treatment of various diseases.
