The word "anaplerosis" is spelled with the IPA phonetic transcription \ˌænəˈpliːroʊsɪs\, which represents the sounds of the letters in the word. This term refers to a metabolic process of replenishing energy stores, which is crucial for maintaining cellular function. Although it may seem complex to spell and pronounce, it has a straightforward meaning in the context of biochemistry. The correct spelling of this word is important for precision in scientific communication and understanding of biological phenomena.
Anaplerosis is a term used in the field of biochemistry and metabolism to describe a vital process that replenishes or fills up depleted metabolic intermediates. It refers to the mechanism by which certain compounds are utilized to replenish the pool of intermediate metabolites that are involved in various metabolic pathways.
In simpler terms, anaplerosis is a process that ensures the availability of key metabolites used in vital metabolic reactions. These intermediates play crucial roles in energy production, amino acid synthesis, and other important biological processes. When these intermediates are depleted due to various reasons, anaplerosis helps to replenish them.
The process of anaplerosis involves the conversion of certain compounds, such as pyruvate or phosphoenolpyruvate, into intermediate metabolites like oxaloacetate or citrate. These intermediates can then enter the tricarboxylic acid (TCA) cycle or other metabolic pathways to replenish the depleted pool.
Anaplerosis is of significant importance in maintaining cellular homeostasis and supporting various metabolic functions. It ensures that the essential building blocks required for cell growth, energy production, and other vital processes are readily available. An understanding of anaplerosis has implications in numerous fields, including disease research, nutrition, and biotechnology, as alterations in anaplerotic pathways can have profound effects on cellular metabolism and overall health.
The form of plastic surgery which consists in the transplantation of tissue to fill a defect resulting from injury or disease.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "anaplerosis" is derived from the Greek term "anaplērōsis" (ἀναπλήρωσις), which is composed of two parts: "ana" (ἀνά), meaning "up" or "again", and "plērōsis" (πλήρωσις), meaning "filling" or "completing". Thus, "anaplerosis" literally translates to "refilling" or "replenishment".