How Do You Spell AMINOHIPPURIC ACID?

Pronunciation: [ɐmˌɪnə͡ʊhɪpjˈʊɹɪk ˈasɪd] (IPA)

Aminohippuric acid, also known as p-aminohippuric acid or PAH, is a substance commonly used in medical tests to measure kidney function. Its spelling can be explained through International Phonetic Alphabet (IPA) transcription as "ə-mee-noh-hi-pyoo-rik" "as-əd". The word is composed of four syllables, with the primary stress falling on "hi" and the secondary stress on "pyur" and "ac". As a complex word, it can be broken down into the root word "amino" and the adjective "hippuric." Overall, the spelling reflects the Greek and Latin roots of the term.

AMINOHIPPURIC ACID Meaning and Definition

1. Aminohippuric acid (also known as para-aminohippuric acid, PAH) is a chemical compound commonly used in medical research and clinical studies to measure renal blood flow and calculate renal plasma flow. It is an analog of the amino acid glycine, with a para-amino group and a carboxylic acid functional group.

   Aminohippuric acid is primarily eliminated from the body by renal secretion. It is actively transported into the renal tubules from the blood by the organic anion transporters located on the basolateral membrane of the tubular cells. This process allows for accurate assessment of renal blood flow, as it is directly related to the renal plasma flow.

   In medical practice, the measurement of aminohippuric acid clearance is considered a gold standard technique for evaluating renal function. It involves injecting a known quantity of the compound into the patient's bloodstream, followed by the collection of timed urine samples. By determining the concentration of aminohippuric acid in these samples and calculating the clearance rate, healthcare professionals can effectively evaluate kidney function.

   Although aminohippuric acid has limited relevance in everyday clinical practice, its use in research and diagnostic procedures has greatly advanced our understanding of renal physiology and the assessment of renal function.

Common Misspellings for AMINOHIPPURIC ACID

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• aminlhippuric acid

Etymology of AMINOHIPPURIC ACID

The term "aminohippuric acid" is derived from several components:

- "Amino" is derived from the Latin word "amino", which means "related to ammonia" or "containing an amino group". It is commonly used in scientific terminology to refer to organic compounds containing an amino group (NH2).

- "Hippuric acid" is derived from the Greek word "hippos", meaning "horse". It was originally isolated from horse urine and named as such. "Hippuric acid" refers to a crystalline compound (C9H9NO3) that is a byproduct of the breakdown of aromatic compounds in the liver.

- Therefore, "Aminohippuric acid" is a combination of "amino" and "hippuric acid".