ALDOLISATION Meaning and
Definition
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Aldolisation refers to a chemical reaction known as the aldol condensation. The term originates from the combination of "aldol" and "ization.” Aldol, derived from aldehyde and alcohol, represents a class of organic compounds containing both a carbonyl group (aldehyde or ketone) and a hydroxyl group. "Ization" signifies the process or act of forming or undergoing a specific reaction.
In chemistry, aldolisation denotes the condensation reaction that occurs between two molecules, commonly an aldehyde and a ketone, to yield a β-hydroxyaldehyde or β-hydroxyketone compound. This reaction typically transpires under basic conditions, involving the removal of a water molecule. The reaction usually takes place via a nucleophilic addition, where the carbonyl group in one molecule acts as an electrophile, and the nucleophilic hydroxyl group of another molecule attacks it.
Aldolisation reactions hold significant importance in organic synthesis as they enable the formation of complex organic compounds with diverse applications. The β-hydroxyaldehydes and β-hydroxyketones produced from such reactions can serve as essential intermediates in the synthesis of pharmaceuticals, natural products, and other organic compounds. Aldolisation reactions can also occur in a self-condensation manner, where a single aldehyde or ketone molecule reacts with itself to yield a dimeric product.
Overall, aldolisation is a chemical process that results in the formation of β-hydroxyaldehydes or β-hydroxyketones, offering valuable synthetic pathways for the creation of intricate organic compounds.
Common Misspellings for ALDOLISATION
- zldolisation
- sldolisation
- wldolisation
- qldolisation
- akdolisation
- apdolisation
- aodolisation
- alsolisation
- alxolisation
- alcolisation
- alfolisation
- alrolisation
- aleolisation
- aldilisation
- aldklisation
- aldllisation
- aldplisation
- ald0lisation
- ald9lisation
- aldokisation
Etymology of ALDOLISATION
The word "aldolisation" is derived from the term "aldol", which refers to a type of organic compound in chemistry. The term "aldol" is actually a combination of two terms, "aldehyde" and "alcohol".
The term "aldehyde" refers to a class of organic compounds that contain a formyl group (-CHO) attached to a carbon atom. On the other hand, "alcohol" refers to a class of organic compounds that contain a hydroxyl group (-OH) attached to a carbon atom.
When two molecules of aldehyde or ketone (containing a carbonyl group) are joined together with the elimination of water, it forms a compound known as an "aldol".
The "-isation" suffix in "aldolisation" indicates the process or action of joining two molecules of aldehyde or ketone to form an aldol compound.
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