ALDOL CONDENSATION Meaning and
Definition
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Aldol condensation is a chemical reaction that involves the combination of two carbonyl compounds to form a larger molecule known as an aldol. It is a type of organic condensation reaction that typically occurs between an aldehyde or ketone with an enol or an enolate ion. This reaction is catalyzed by a base, such as hydroxide or alkoxide ions, and requires the presence of an α-hydrogen, which can easily form a reactive enolate ion.
During an aldol condensation, the α-hydrogen of the carbonyl compound is deprotonated by the base, generating a nucleophilic enolate ion. This enolate ion then attacks the electrophilic carbon of another carbonyl compound, resulting in the formation of a carbon-carbon bond. The resulting intermediate is an aldol, which contains both an alcohol and an aldehyde or ketone functional group. This aldol molecule can exist in two different forms - the syn-aldol or the anti-aldol - depending on the orientation of the substituents.
Further reactions, such as dehydration or elimination, can occur after the aldol condensation to form α,β-unsaturated carbonyl compounds or various other products. The aldol condensation is an important reaction in organic chemistry as it allows the synthesis of complex molecules and is often employed in the production of pharmaceuticals, natural products, and synthetic polymers.
Common Misspellings for ALDOL CONDENSATION
- zldol condensation
- sldol condensation
- wldol condensation
- qldol condensation
- akdol condensation
- apdol condensation
- aodol condensation
- alsol condensation
- alxol condensation
- alcol condensation
- alfol condensation
- alrol condensation
- aleol condensation
- aldil condensation
- aldkl condensation
- aldll condensation
- aldpl condensation
- ald0l condensation
- ald9l condensation
- aldok condensation
Etymology of ALDOL CONDENSATION
The term "aldol condensation" comes from the combination of two parts: "aldol" and "condensation".
The word "aldol" originates from the combination of "aldehyde" and "alcohol". Aldol molecules contain both aldehyde and alcohol functional groups. The aldol reaction, which precedes the aldol condensation, involves the formation of an aldol compound through the addition of an enol or enolate to an aldehyde or ketone.
The word "condensation" refers to a chemical reaction in which two or more molecules combine, leading to the formation of a larger molecule and the loss of a smaller molecule (usually water or an alcohol). In the case of the aldol condensation, the smaller molecule lost is usually water.
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