How Do You Spell ALCOHOL DEHYDROGENASE II?

Pronunciation: [ˈalkəhˌɒl dˌiːha͡ɪdɹˈə͡ʊd͡ʒne͡ɪs ɹˌə͡ʊmən tˈuː] (IPA)

Alcohol Dehydrogenase II is a crucial enzyme in the human body responsible for metabolizing alcohol. The spelling of this word can be challenging due to its technicality. It is pronounced as /ˈælkəhɒl, diːhaɪˈdrɒdʒəneɪz, tuː/ in IPA phonetic transcription. The first syllable is pronounced as "al-ko-hol," the second is "dee-hy-dro-gen-ase," and the third is "too." The use of IPA phonetic transcription helps explain the spelling of this complex term and ensures accuracy in pronunciation.

ALCOHOL DEHYDROGENASE II Meaning and Definition

1. Alcohol dehydrogenase II is an enzyme that plays a crucial role in the metabolism of alcohol within the human body. It is primarily active in the liver, where it catalyzes the conversion of alcohol into acetaldehyde. This enzyme is part of the alcohol dehydrogenase family and is encoded by the ADH1B gene.

   The reaction facilitated by alcohol dehydrogenase II involves the transfer of hydrogen from alcohol to the enzyme's coenzyme, NAD+. This process results in the oxidation of alcohol to acetaldehyde, a toxic compound that accumulates in the body when alcohol consumption exceeds the liver's capacity to metabolize it further.

   The genetic variation of ADH1B gene can have significant effects on an individual's alcohol tolerance and susceptibility to alcohol-related diseases. Certain variants of this gene, particularly the ADH1B*2 and ADH1B*3 alleles which are commonly found in East Asian populations, code for more efficient forms of alcohol dehydrogenase II. These variants allow for faster conversion of alcohol into acetaldehyde, leading to a buildup of this toxic compound in the body. As a result, individuals with these variants may experience unpleasant symptoms such as facial flushing, rapid heartbeat, and nausea after consuming alcohol, making them less prone to heavy drinking.

   In conclusion, alcohol dehydrogenase II is the enzyme responsible for metabolizing alcohol in the liver. Genetic variations of this enzyme can influence an individual's alcohol tolerance and their susceptibility to alcohol-related health issues.

Common Misspellings for ALCOHOL DEHYDROGENASE II

• zlcohol dehydrogenase ii
• slcohol dehydrogenase ii
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• alfohol dehydrogenase ii
• aldohol dehydrogenase ii
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• alcphol dehydrogenase ii
• alc0hol dehydrogenase ii
• alc9hol dehydrogenase ii
• alcogol dehydrogenase ii
• alcobol dehydrogenase ii
• alconol dehydrogenase ii