AGGLUTINATION TEST Meaning and
Definition
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An agglutination test is a diagnostic method used in laboratory settings for identifying and detecting the presence of certain substances or organisms in a given sample. It is based on the principle of agglutination, which refers to the clumping together of particles or cells when they come into contact with specific antibodies or antigens.
In an agglutination test, a sample is typically mixed with a suspension of particles or cells that have been coated with a specific antibody or antigen. If the target substance is present in the sample, it will bind to the coated particles or cells, causing them to clump together or form visible aggregates.
This clumping reaction can be visually observed or quantified using various methods, such as turbidity measurement, microscopy, or specialized instruments. The presence and degree of agglutination are indicative of the presence and concentration of the target substance in the sample.
Agglutination tests are widely used in medical diagnostics, as they provide rapid and reliable results for a variety of purposes. They are commonly employed for blood typing, identification of infectious agents (bacteria, viruses, or parasites), autoimmune disease detection, and detection of antibodies or antigens in biological samples.
Overall, agglutination tests offer a valuable tool in laboratory medicine, enabling the detection and identification of specific substances to aid in diagnosis, treatment, and monitoring of various diseases and conditions.
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A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
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Etymology of AGGLUTINATION TEST
The word "agglutination" comes from the Latin word "agglutinare", which means "to glue together" or "to stick together". In the context of science and medicine, it refers to the clumping or sticking together of particles or cells in a solution.
The word "test" is derived from the Latin word "testum", which means "earthen pot" or "a witness". Over time, "test" evolved to refer to a method or procedure to determine or reveal something.
Therefore, the term "agglutination test" refers to a diagnostic method or procedure that examines the clumping or sticking together of particles or cells as a means of identifying specific substances, such as antibodies or antigens, in a solution.
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