Adrenal Rest Tumors are a type of tumor that can occur in individuals with congenital adrenal hyperplasia (CAH). The spelling of "adrenal" is pronounced /əˈdriːn(ə)l/ in IPA phonetic transcription, with emphasis on the second syllable. "Rest" is pronounced /rɛst/, and "tumors" is pronounced /ˈtjuːməz/. The term "adrenal rest tumors" refers to tumors that develop from cells left behind during fetal development, which later can grow and cause symptoms such as abdominal pain or menstrual irregularities. Treatment typically involves surgery to remove the affected tissue.
Adrenal rest tumors, also known as adrenal rest hyperplasia or accessory adrenal tissue, are uncommon benign tumors that can occur in various locations of the body. These tumors typically arise from remnants of adrenal tissue that are mistakenly left behind during embryonic development. Adrenal tissue is primarily found in the adrenal glands, which are small, triangular-shaped organs located on top of the kidneys. However, during fetal development, some adrenal cells may remain in other parts of the body, such as the abdomen or the gonads.
Adrenal rest tumors are typically asymptomatic and are usually discovered incidentally during imaging tests or surgical procedures. They are commonly found in the vicinity of the adrenal glands, such as in the adrenal bed, kidney, or retroperitoneal area. However, they can also occur in other locations, such as the liver, lung, or even the testicles or ovaries.
These tumors are usually non-cancerous, but they can grow in size and potentially cause compression or displacement of nearby organs, leading to symptoms such as pain or urinary problems. Treatment options for adrenal rest tumors may vary depending on their location and size. In some cases, surgical removal of the tumor may be recommended, especially if it causes significant symptoms or if there is concern about malignancy.
Overall, adrenal rest tumors are rare and often benign growths that originate from residual adrenal tissue found outside of the adrenal glands. Although generally asymptomatic, they can occasionally become clinically significant and require intervention.