How Do You Spell ADENYLATE KINASE?

Pronunciation: [ˈadənˌɪle͡ɪt kˈɪne͡ɪs] (IPA)

Adenylate Kinase is a scientific term that refers to an enzyme that catalyzes the transfer of a phosphate group from ATP to AMP. The spelling of this word adheres to the rules of the International Phonetic Alphabet. The first syllable, "a-den", is pronounced with a short vowel sound, while the second syllable, "y-late", uses a long "i" sound. The final syllable, "ki-nase", rhymes with "base" and is pronounced using a long "a" sound. In scientific terms, proper spelling and pronunciation are crucial to accurately convey information and avoid confusion.

ADENYLATE KINASE Meaning and Definition

1. Adenylate kinase is an enzyme that plays a crucial role in cellular energy metabolism. It catalyzes the reversible transfer of a phosphate group between adenosine diphosphate (ADP) and adenosine triphosphate (ATP). This enzymatic reaction is often represented as:

   ADP + ATP ⇌ 2 ADP

   The reaction facilitated by adenylate kinase enables the efficient transfer of energy within the cell. In situations where cellular activity demands exceed the energy available from ATP, adenylate kinase steps in to aid energy transfer by converting one molecule of ATP into two molecules of ADP. Conversely, in situations where ATP levels are high and ADP levels are low, adenylate kinase reverses the reaction to synthesize ATP from ADP.

   Adenylate kinase is found in various tissues and organs, including the brain, heart, skeletal muscles, and liver. Its presence highlights its widespread importance in cellular energy homeostasis. This enzyme is characterized by its high affinity for both ATP and ADP, ensuring efficient energy transfer between these nucleotides.

   Mutations in the gene encoding adenylate kinase have been linked to several diseases, including a genetic disorder called phosphoglycerate kinase deficiency. This condition affects the enzyme responsible for another step in energy metabolism, leading to various symptoms such as muscle weakness, intellectual disability, and hemolytic anemia.

   In summary, adenylate kinase is an enzyme crucial in cellular energy metabolism. It enables the transfer of a phosphate group between ATP and ADP, assisting in the efficient utilization and generation of energy within the cell.

Common Misspellings for ADENYLATE KINASE

• zdenylate kinase
• sdenylate kinase
• wdenylate kinase
• qdenylate kinase
• asenylate kinase
• axenylate kinase
• acenylate kinase
• afenylate kinase
• arenylate kinase
• aeenylate kinase
• adwnylate kinase
• adsnylate kinase
• addnylate kinase
• adrnylate kinase
• ad4nylate kinase
• ad3nylate kinase
• adebylate kinase
• ademylate kinase
• adejylate kinase
• adehylate kinase

Etymology of ADENYLATE KINASE

The word "adenylate kinase" comes from the combination of two terms: adenylate and kinase.

1. Adenylate: The term "adenylate" refers to a nucleotide called adenosine monophosphate (AMP). Adenylate comes from the combination of the word "adenine" (a type of nitrogenous base found in DNA and RNA) and "-ylate" (a suffix indicating the presence of a phosphate group). Adenosine monophosphate is one of the building blocks of nucleic acids and plays a role in energy metabolism.

2. Kinase: The term "kinase" refers to an enzyme that catalyzes the transfer of a phosphate group from a donor molecule to a acceptor molecule. It comes from the Greek word "kinēsis", meaning movement or motion.