Acathectic jaundice, also known as nutritional jaundice or obstructive jaundice, is a condition characterized by the yellow discoloration of the skin, white of the eyes, and mucous membranes due to an obstruction in the flow of bile from the liver. This type of jaundice is caused by insufficient intake or absorption of essential nutrients, particularly fat-soluble vitamins, that are necessary for the functioning of the liver and biliary system.
The term "acathectic" refers to the lack of appetite or aversion to food that is commonly associated with this condition. The reduced or impaired appetite leads to a decreased intake of nutrients, specifically fat-soluble vitamins A, D, E, and K, which are crucial for maintaining normal liver function.
The obstruction of bile flow can result from various factors such as gallstones, tumors, or inflammation in the liver, bile ducts, or pancreas. When the obstruction occurs, bilirubin, a yellow pigment produced during the normal breakdown of red blood cells, builds up in the bloodstream rather than being eliminated through the bile. This accumulation of bilirubin leads to the yellowing of the skin, eyes, and other tissues.
Symptoms of acathectic jaundice include yellowing of the skin, fatigue, weakness, abdominal pain, nausea, dark urine, and pale stools. Treatment involves addressing the underlying cause of the obstruction and replenishing the nutrient deficiencies through dietary modifications or supplementation.
Prompt medical attention is essential to diagnose the cause of acathectic jaundice and determine the appropriate treatment plan to alleviate symptoms, prevent complications, and restore proper liver function.
