Yaba monkey tumor virus is a viral infection that primarily affects monkeys, most commonly the African green monkey (also known as the vervet monkey) and the rhesus macaque. This virus belongs to the family Herpesviridae and the subfamily Alphaherpesvirinae, specifically the genus Simplexvirus.
Yaba monkey tumor virus is named after the location in Nigeria where the virus was first isolated, the Yaba district in Lagos. It is also commonly referred to as YMTV. This virus has been extensively studied due to its ability to induce tumors and cause diseases in primates.
Infection with Yaba monkey tumor virus often leads to the formation of multiple tumors in various organs of the infected monkeys. These tumors commonly arise in the liver, spleen, and lymph nodes. Infected animals may exhibit clinical signs such as an enlarged spleen, liver dysfunction, and lymphoid hyperplasia.
YMTV is primarily transmitted through direct contact with infected bodily fluids, such as saliva or blood, of monkeys carrying the virus. It can also be transmitted through contaminated instruments or fomites. However, it is important to note that YMTV is not known to naturally infect humans and poses a minimal risk to human health.
Research on Yaba monkey tumor virus has played a crucial role in understanding the biology and pathogenesis of herpesviruses. Studying this virus has provided valuable insights into tumor development and immune response modulation, contributing to advancements in virology and oncology.
