The word "xanthochromia" refers to the yellow coloration of cerebrospinal fluid due to the presence of bilirubin or blood breakdown products. The IPA phonetic transcription for this word is /ˌzænθoʊˈkroʊmiə/. The initial "x" is pronounced as a /z/ sound and the "ch" is pronounced as a /k/ sound. The vowel combinations "o" and "io" in the word are pronounced as a long /o/ sound, and the final "-ia" is pronounced as /iə/. The unique spelling of xanthochromia may make it difficult to spell and pronounce for some individuals.
Xanthochromia is a medical term used to refer to a condition characterized by the presence of yellow discoloration in the cerebrospinal fluid (CSF). This discoloration is visible when examining the CSF in a clear tube or collecting it in a glass container. The term is derived from the Greek words xanthos, meaning yellow, and chroma, meaning color.
The yellow coloration in the CSF is primarily caused by the breakdown of red blood cells and the subsequent release of bilirubin, a yellow pigment found in bile. Xanthochromia is often observed after bleeding in the subarachnoid space, which is the area between the brain and the thin tissues that cover it. Subarachnoid hemorrhage, resulting from ruptured cerebral aneurysms, trauma to the head, or other causes, can lead to the presence of blood in the CSF. Over time, the breakdown of red blood cells in the CSF causes xanthochromia.
Xanthochromia is commonly evaluated as part of a diagnostic workup to identify the presence and extent of bleeding in the central nervous system. By assessing the color of the CSF, healthcare professionals can differentiate between recent and older bleeding, as xanthochromia indicates that the blood has had time to break down. This information contributes to the diagnosis and management of various conditions affecting the brain and spinal cord, such as subarachnoid hemorrhage, head trauma, or infectious diseases.
The occurrence of patches of yellow color in the skin, resembling xanthoma, but without the nodules or plates.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "xanthochromia" is derived from two Greek words: "xanthos" meaning "yellow" and "khromos" meaning "color".