How Do You Spell WILMS TUMOR GENE?

Pronunciation: [wˈɪlmz tjˈuːmə d͡ʒˈiːn] (IPA)

The Wilms Tumor Gene, also known as WT1, is a gene that plays a critical role in the development of the kidneys. The spelling of this word is relatively straightforward: [wɪlmz tuːmər dʒiːn]. The "W" is pronounced as the letter, "i" sounds as in "sit," the "l" as in "lion," and the "m" as in "mother." The stress is on the first syllable, with the "tumor" emphasized. The "e" at the end is silent, making the final syllable "n" pronounced as "in."

Meaning and Definition
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WILMS TUMOR GENE Meaning and Definition

  1. The Wilms tumor gene refers to a specific gene called WT1, which is associated with the development of Wilms tumor, a type of kidney cancer that occurs predominantly in children. The term "Wilms tumor gene" is used to specifically denote the genetic component involved in the formation of this cancer.

    The WT1 gene is responsible for encoding a protein that plays a crucial role in the development of various tissues and organs during embryonic growth. In individuals with an inherited mutation or alteration in the WT1 gene, there is an increased susceptibility to developing Wilms tumor. This gene is known to be involved in regulating the growth and division of cells, as well as influencing their differentiation into various specialized cell types within the kidney.

    The presence of a mutated WT1 gene disrupts the normal development and growth of kidney cells, leading to the formation of a tumor. Although its exact mechanism is not fully understood, research suggests that the WT1 gene mutation affects the balance between cell proliferation and programmed cell death, leading to uncontrolled cell growth and the formation of tumors.

    Understanding the role of the Wilms tumor gene is crucial for diagnosing and treating individuals at a higher risk of developing Wilms tumor. Genetic testing can help identify mutations in the WT1 gene, enabling close monitoring and preventative measures for affected individuals. Moreover, studying this gene allows researchers to gain insights into the underlying mechanisms of tumor development and potentially develop targeted therapies for preventing or treating Wilms tumor.

Common Misspellings for WILMS TUMOR GENE

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