VUS Meaning and
Definition
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VUS is an acronym that stands for "Variant of Uncertain Significance." It is a term used in the field of genetics and genomics to describe a specific type of genetic variant that is found in an individual's DNA sequence but whose impact on health and disease is not yet well understood.
In genetic testing and research, scientists analyze an individual's DNA to identify any genetic variations or mutations that may be associated with certain diseases or conditions. These variations can be classified into different categories based on their significance. VUS is one such category that indicates a lack of clear understanding about the potential health effects of the genetic variant.
When a genetic variant is identified as a VUS, it means that there is insufficient evidence to determine whether the variant is harmful or benign. It could potentially be associated with a higher risk of developing a particular condition or disease, or it may have no significant impact at all. More research and evidence are needed to establish a definitive classification for the variant.
Medical professionals and genetic counselors often communicate the presence of a VUS to individuals who have undergone genetic testing. They provide information about the variant's current understanding and emphasize the need for further investigation and monitoring. As technology advances and more data becomes available, some VUSs may eventually be reclassified as either pathogenic (harmful) or benign, providing clearer insights into their clinical significance.
Common Misspellings for VUS
- v7s
- vfus
- vyus
- vuhs
- v8us
- vu8s
- v7us
- vu7s
- vuas
- vuzs
- vusz
- vuxs
- vusx
- vusd
- vuws
- vusw
- vvus
- v us
- vu s
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