How Do You Spell VKH SYNDROME?

Pronunciation: [vˌiːkˌe͡ɪˈe͡ɪt͡ʃ sˈɪndɹə͡ʊm] (IPA)

VKH Syndrome, also known as Vogt-Koyanagi-Harada Syndrome, is an autoimmune disorder that affects the eyes, skin, and meninges of the central nervous system. The spelling of this word can be explained using the International Phonetic Alphabet (IPA) as /voʊt koʊˌjɑːnədʒi həˈrɑːdə sɪnˌdroʊm/. The phonetic transcription helps to clarify the pronunciation of the word by breaking it down into its individual sounds. This can be helpful for individuals who are unfamiliar with the correct pronunciation of medical terminology.

VKH SYNDROME Meaning and Definition

1. VKH Syndrome, also known as Vogt-Koyanagi-Harada Syndrome, is a rare autoimmune disorder primarily affecting the eye, as well as other systems of the body. It is characterized by a combination of symptoms including bilateral uveitis, inflammation of the eye, as well as neurological, auditory, and integumentary manifestations.

   The uveitis associated with VKH Syndrome is characterized by inflammation of the uvea, the middle layer of the eye. This inflammation can lead to various symptoms such as blurred vision, eye pain, redness, and sensitivity to light. In some cases, it may progress to more severe complications such as vision loss or glaucoma if not managed promptly.

   Apart from ocular findings, VKH Syndrome also involves neurological symptoms like headaches, meningismus, and changes in mental status. Auditory manifestations such as tinnitus and hearing loss may also occur. Additionally, integumentary manifestations including skin and hair changes, like vitiligo and poliosis (localized hair depigmentation), can be present.

   VKH Syndrome is thought to result from an abnormal immune response where the body's immune system mistakenly attacks the melanocytes (pigment-producing cells) in various tissues, including the eyes, inner ear, skin, and meninges. Although the exact cause of VKH Syndrome is unclear, it is believed to have a genetic predisposition and often follows a viral infection or trauma.

   Management of VKH Syndrome usually involves a multidisciplinary approach, including ophthalmologists, dermatologists, and neurologists. Treatment primarily aims to control inflammation through the use of corticosteroids and immunosuppressive medications. Early diagnosis and prompt initiation of treatment are crucial for minimizing complications and preserving visual acuity.

Common Misspellings for VKH SYNDROME

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Etymology of VKH SYNDROME

The acronym "VKH" stands for Vogt-Koyanagi-Harada, which is named after the three ophthalmologists who first described the syndrome. It was named after Ernst Vogt, a German ophthalmologist, and Yoshizo Koyanagi and Einosuke Harada, two Japanese ophthalmologists, who independently reported cases of a similar inflammatory condition affecting the eyes, skin, and other organs. The syndrome was initially described in the early 20th century, and since then, it has been known as Vogt-Koyanagi-Harada Syndrome or VKH Syndrome in honor of these physicians.