VENTRICLE REMODELINGS Meaning and
Definition
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Ventricular remodeling refers to the structural and functional changes that occur within the ventricles of the heart. Specifically, it pertains to alterations in the shape, size, and composition of the ventricular chambers in response to various physiological or pathological stimuli.
In a healthy heart, ventricular remodeling may occur as a natural adaptation to exercise or physical training. This type of remodeling is known as physiological ventricular remodeling and is characterized by an increase in size and thickness of the ventricular walls, allowing for enhanced contractility and increased cardiac output during physical exertion.
On the other hand, pathological ventricular remodeling occurs as a result of certain diseases or conditions, such as heart failure, myocardial infarction (heart attack), hypertension, or valvular heart disease. In this context, ventricular remodeling refers to maladaptive changes that negatively impact cardiac function. It involves alterations in the extracellular matrix, cellular structure, and signaling pathways, leading to cardiac hypertrophy (enlargement of the heart), fibrosis (excessive deposition of collagen), chamber dilation, and impaired contractility.
Ventricular remodeling can have significant clinical implications, as it often contributes to the progression of cardiovascular diseases, compromises heart function, and increases the risk of complications such as arrhythmias, heart failure, and sudden cardiac death. Understanding the mechanisms underlying ventricular remodeling is crucial for developing effective therapeutic strategies aimed at reversing, preventing, or mitigating adverse cardiac remodeling processes.
Common Misspellings for VENTRICLE REMODELINGS
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Etymology of VENTRICLE REMODELINGS
The term "ventricle remodelings" is derived from the combination of two words: "ventricle" and "remodeling".
1. Ventricle: The word "ventricle" originates from the Latin word "ventriculus", meaning a small belly or cavity. It was first used in English around the 15th century to refer to a hollow chamber within an organ, specifically in relation to the heart. In the context of human anatomy, the heart has four chambers: two atria and two ventricles. The ventricles are the lower chambers responsible for pumping blood to the body and lungs.
2. Remodeling: The word "remodeling" is coined from the verb "remodel", which is a combination of "re-" (meaning again) and "model" (a representation or design).
