The term "variola pemphigosa" is a medical term used to describe a type of smallpox. The spelling of this word is based on its pronunciation, which is broken down through its IPA phonetic transcription. The first syllable is pronounced "vəˈraɪələ," and the second syllable is "pɛmfɪˈgoʊsə." The "v" sound in the first syllable represents the voiced labiodental fricative, while the "g" sound in the second syllable represents the voiced velar stop. Understanding the phonetic transcription of the word helps to ensure accurate pronunciation for medical professionals and patients alike.
Variola pemphigosa is a rare and severe form of smallpox that causes the formation of large, fluid-filled blisters or vesicles on the skin. It is an extremely contagious and potentially life-threatening viral infection, caused by the variola virus, which primarily affects humans.
The clinical presentation of variola pemphigosa is characterized by fever, malaise, headache, and intense body aches, which are followed by the appearance of multiple painful lesions. These lesions are typically deep-seated and progress rapidly to form large, raised blisters that are filled with clear fluid. The blisters are usually surrounded by an area of redness and inflammation and may be accompanied by severe itching.
The vesicles eventually expand and coalesce, forming large irregular-shaped blisters or bullae. These bullae are fragile and can easily rupture, resulting in the exposure of raw and eroded skin underneath. Consequently, variola pemphigosa can cause severe pain and discomfort to affected individuals.
While the overall mortality rate of variola pemphigosa is relatively high, complications can arise due to secondary bacterial infections, such as cellulitis or sepsis, which can further increase the risk of morbidity and mortality.
Variola pemphigosa historically posed a significant public health threat, particularly during smallpox epidemics. However, due to the worldwide success of smallpox eradication efforts and the absence of natural cases since 1977, variola pemphigosa is now considered a disease of historical relevance.
A form of smallpox in which the eruption consists of pemphigus-like blebs.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "variola" originates from Latin, derived from "varus" meaning "pimply" or "blemished". It specifically refers to the smallpox virus.
"Pemphigosa" comes from the Greek word "pémphix" meaning "blister". It is a term used to describe a severe form of pemphigus, an autoimmune blistering disorder.
Therefore, "variola pemphigosa" combines the Latin term for smallpox with the Greek term for a severe blistering condition, suggesting a severe form of blistering that may occur with smallpox infection.