How Do You Spell VALINE TRNA LIGASE?

Pronunciation: [vˈe͡ɪla͡ɪn tˈiː ˌɑːɹˌɛnˈe͡ɪ lˈɪɡe͡ɪs] (IPA)

The correct spelling for the word "Valine tRNA Ligase" is /ˈvælɪn tiː ɑːr ɛn eɪ ˈlaɪgeɪs/. This means the first syllable is pronounced as "val," followed by a short "i" sound in "ine." The "tRNA" portion is pronounced with a long "e" sound followed by a glottal stop, while "ligase" is pronounced with a long "i" sound and a short "e" sound. This word refers to an enzyme that catalyzes the formation of a covalent bond between valine and transfer RNA.

Meaning and Definition
Common Misspellings
Basic Check Advanced Check

VALINE TRNA LIGASE Meaning and Definition

  1. Valine tRNA ligase is an enzyme that belongs to the class of ligases. Ligases are a type of enzyme that catalyze the joining of two molecules through the formation of a covalent bond. Valine tRNA ligase specifically serves the role of catalyzing the formation of a covalent bond between the amino acid valine and its corresponding transfer ribonucleic acid (tRNA) molecule during protein synthesis.

    During translation, valine tRNA ligase plays a crucial role in ensuring the accurate incorporation of valine into a growing polypeptide chain based on the messenger RNA (mRNA) template. It accomplishes this by recognizing the specific valine-carrying tRNA molecule and utilizing energy from adenosine triphosphate (ATP) hydrolysis to activate valine, creating an aminoacyl-AMP intermediate. The enzyme then transfers the activated valine to the 3'-terminal adenosine of the tRNA molecule, forming a high-energy valyl-tRNA complex.

    This valyl-tRNA complex can then participate in the ribosome-mediated synthesis of polypeptides by mRNA decoding, ultimately leading to the accurate incorporation of valine into the growing protein chain. Valine tRNA ligase is essential for proper protein synthesis, as any errors or deficiencies in its activity can potentially lead to the production of faulty proteins, disrupting cellular functions and impacting overall organismal health.

    In summary, valine tRNA ligase is an enzyme that specifically catalyzes the formation of a covalent bond between the amino acid valine and its corresponding tRNA molecule, ensuring accurate incorporation of valine during protein synthesis.

Common Misspellings for VALINE TRNA LIGASE

  • caline trna ligase
  • baline trna ligase
  • galine trna ligase
  • faline trna ligase
  • vzline trna ligase
  • vsline trna ligase
  • vwline trna ligase
  • vqline trna ligase
  • vakine trna ligase
  • vapine trna ligase
  • vaoine trna ligase
  • valune trna ligase
  • valjne trna ligase
  • valkne trna ligase
  • valone trna ligase
  • val9ne trna ligase
  • val8ne trna ligase
  • valibe trna ligase
  • valime trna ligase
  • valije trna ligase