V FMS ONCOGENES Meaning and
Definition
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V-fms oncogenes are a group of oncogenes that are derived from the feline sarcoma virus (FMS). These oncogenes encode for a cell surface receptor known as the fms proto-oncogene, which belongs to the receptor tyrosine kinase family. The v-fms oncogenes are viral genes that have been acquired by the FMS virus through the capture and integration of a host-cell proto-oncogene.
The activation of v-fms oncogenes results in the continuous stimulation of cell growth and division, leading to the formation of tumors. The v-fms oncogenes encode for a constitutively active form of the fms receptor tyrosine kinase, which signals without the requirement for ligand binding. This constitutive activation of the receptor promotes unregulated cell proliferation and survival, bypassing the normal regulatory mechanisms that control cellular growth.
The v-fms oncogenes have been extensively studied in animal models and have provided valuable insights into the molecular mechanisms underlying cancer development. Their study has helped in understanding the role of receptor tyrosine kinases in cellular signaling pathways, as well as in the design and development of targeted therapies against cancers.
Overall, v-fms oncogenes represent a class of viral oncogenes that play a crucial role in the development of tumors by promoting uncontrolled cell growth and survival through the constitutive activation of the fms receptor tyrosine kinase.
Common Misspellings for V FMS ONCOGENES
- c fms oncogenes
- b fms oncogenes
- g fms oncogenes
- f fms oncogenes
- v dms oncogenes
- v cms oncogenes
- v vms oncogenes
- v gms oncogenes
- v tms oncogenes
- v rms oncogenes
- v fns oncogenes
- v fks oncogenes
- v fjs oncogenes
- v fma oncogenes
- v fmz oncogenes
- v fmx oncogenes
- v fmd oncogenes
- v fme oncogenes
- v fmw oncogenes
- v fms incogenes
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