UNIPARENTAL HETERODISOMIES Meaning and
Definition
-
Uniparental heterodisomies are genetic abnormalities that occur when an individual inherits both copies of a specific chromosome or section of a chromosome from only one parent, instead of one copy from each parent. This phenomenon results in a loss of heterozygosity, meaning that the individual has two copies of the same allele or gene variant.
Uniparental heterodisomies can arise through two distinct mechanisms. First, there can be an error during meiosis, the process of cell division that produces eggs and sperm. This may result in two copies of a specific chromosome from one parent being incorporated into the reproductive cells. Second, uniparental heterodisomies can occur as a consequence of mitotic recombination, which is a genetic rearrangement that takes place during early embryonic development and can lead to the presence of two maternally or paternally derived chromosomes in certain cells of the body.
These genetic abnormalities can have significant implications for an individual's health because they disrupt the normal balance of genes that are typically derived from both parents. Uniparental heterodisomies can cause a range of congenital disorders, altered gene expression patterns, or even produce traits resembling recessive disorders due to the loss of one parental copy of a chromosome or segment.
The identification of uniparental heterodisomies has been facilitated by advances in genetic testing technologies. Understanding these genetic abnormalities is crucial for the diagnosis, management, and counseling of affected individuals and their families.
Common Misspellings for UNIPARENTAL HETERODISOMIES
- yniparental heterodisomies
- hniparental heterodisomies
- jniparental heterodisomies
- iniparental heterodisomies
- 8niparental heterodisomies
- 7niparental heterodisomies
- ubiparental heterodisomies
- umiparental heterodisomies
- ujiparental heterodisomies
- uhiparental heterodisomies
- unuparental heterodisomies
- unjparental heterodisomies
- unkparental heterodisomies
- unoparental heterodisomies
- un9parental heterodisomies
- un8parental heterodisomies
- unioarental heterodisomies
- unilarental heterodisomies
- uni-arental heterodisomies
- uni0arental heterodisomies
Etymology of UNIPARENTAL HETERODISOMIES
The term "Uniparental Heterodisomies" consists of multiple components:
1. "Uni-" is a prefix derived from the Latin word "unus", meaning "one" or "single". In this context, it implies that only one parent is involved.
2. "Parental" is an adjective form of the noun "parent", which refers to an individual who gives birth to or raises a child. In genetics, it denotes a characteristic or condition passed from a parent to an offspring.
3. "Heterodisomies" is a combination of two terms: "hetero-" and "disomies".
- "Hetero-" comes from the Greek word "heteros", meaning "different" or "other". It implies dissimilarity or variation.
Infographic
Add the infographic to your website:
