How Do You Spell UDP ACETYLMURAMIC ACID?

Pronunciation: [jˌuːdˌiːpˈiː ˌasɪtˌɪlmjʊɹˈamɪk ˈasɪd] (IPA)

UDP Acetylmuramic Acid is a complex chemical compound commonly found in bacterial cell walls. It is a mouthful to pronounce and spell due to its long scientific name. The IPA phonetic transcription of the word goes like this: /juːdiːpiː əˌsɛtɪlˌmjʊərəˈmeɪɪk ˈæsɪd/. As can be seen from the transcription, the word comprises of several syllables, including long and short vowels, and a mix of consonants. Proper pronunciation and spelling of this term is crucial in the field of microbiology to avoid confusion and miscommunication.

UDP ACETYLMURAMIC ACID Meaning and Definition

  1. UDP Acetylmuramic Acid (UDP-MurNAc) is a chemical compound that plays a crucial role in bacterial cell wall synthesis. It is a nucleotide sugar that acts as a building block for the formation of peptidoglycan, an essential component of the cell wall in many bacteria.

    Acetylmuramic acid is formed by the condensation of N-acetylglucosamine (GlcNAc) and phosphoenolpyruvate (PEP) through the action of the enzyme MurA. This reaction is an early step in the biosynthesis of UDP-MurNAc. UDP-MurNAc then serves as a precursor for the synthesis of peptidoglycan, which is responsible for maintaining bacterial cell shape, providing rigidity, and protecting against osmotic stress.

    In the process of peptidoglycan synthesis, UDP-MurNAc is enzymatically converted to UDP-N-acetylmuramate pentapeptide by the sequential addition of amino acids. Subsequently, this pentapeptide is transferred to a lipid carrier molecule, called undecaprenyl phosphate, on the cytoplasmic side of the cell membrane. The lipid-bound peptidoglycan precursor is then translocated across the membrane, where it is incorporated into the growing cell wall.

    UDP Acetylmuramic Acid serves as a critical intermediate in the biosynthesis of the bacterial cell wall, making it an attractive target for the development of antimicrobial agents. Inhibiting enzymes involved in the production of UDP-MurNAc disrupts peptidoglycan synthesis, resulting in bacterial cell wall defects and ultimately leading to bacterial cell death.

Common Misspellings for UDP ACETYLMURAMIC ACID

  • ydp acetylmuramic acid
  • hdp acetylmuramic acid
  • jdp acetylmuramic acid
  • idp acetylmuramic acid
  • 8dp acetylmuramic acid
  • 7dp acetylmuramic acid
  • usp acetylmuramic acid
  • uxp acetylmuramic acid
  • ucp acetylmuramic acid
  • ufp acetylmuramic acid
  • urp acetylmuramic acid
  • uep acetylmuramic acid
  • udo acetylmuramic acid
  • udl acetylmuramic acid
  • ud- acetylmuramic acid
  • ud0 acetylmuramic acid
  • udp zcetylmuramic acid
  • udp scetylmuramic acid
  • udp wcetylmuramic acid
  • udp qcetylmuramic acid