TUMOR ANGIOGENESIS Meaning and
Definition
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Tumor angiogenesis refers to the process of the growth and formation of new blood vessels that supply a tumor with oxygen and nutrients. It is a critical step in tumor development and progression, as without the formation of new blood vessels, tumors would not be able to grow beyond a certain size. Angiogenesis is a natural process that occurs in our bodies to support normal tissue growth and repair, such as during wound healing. However, in the case of tumor angiogenesis, this process becomes abnormal and uncontrolled.
Tumor angiogenesis is stimulated by various factors produced by the tumor cells themselves, as well as surrounding cells in the tumor microenvironment. These factors include proteins called angiogenic growth factors, such as vascular endothelial growth factor (VEGF). These growth factors promote the growth of endothelial cells, which line the inside of blood vessels. As a result, new blood vessels sprout from existing ones and infiltrate into the tumor, providing essential nutrients and oxygen.
The process of tumor angiogenesis is complex and involves the interaction of many signaling pathways and molecules. Understanding this process has led to the development of anti-angiogenic therapies, which aim to inhibit the formation of new blood vessels and stifle tumor growth. These therapies can be used in combination with other cancer treatments, such as chemotherapy or radiation therapy, to improve treatment outcomes.
Common Misspellings for TUMOR ANGIOGENESIS
- rumor angiogenesis
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Etymology of TUMOR ANGIOGENESIS
The word "tumor angiogenesis" is derived from two components: "tumor" and "angiogenesis".
1. Tumor: The term "tumor" comes from the Latin word "tumor" which means "swelling" or "a lump". It was originally used to describe any kind of swelling or abnormal growth in the body.
2. Angiogenesis: The term "angiogenesis" is a combination of two Greek words - "angeion", meaning "vessel", and "genesis", meaning "origin" or "birth". It refers to the formation of new blood vessels from preexisting ones, a process that occurs during various physiological and pathological conditions.
When these two components are combined to form "tumor angiogenesis", it specifically refers to the formation of new blood vessels within or around a tumor, which is a characteristic feature of tumor growth and progression.
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