TRANSFUSION TRANSMITTED VIRUS Meaning and
Definition
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Transfusion Transmitted Virus (TTV) is a distinct group of small, non-enveloped DNA viruses that are known to be transmitted through blood transfusions or organ transplants. These viruses belong to the family Anelloviridae and constitute a diverse group of viral strains that share certain common genetic characteristics. TTVs have been found in various bodily fluids such as blood, saliva, and semen.
TTV was first identified in the late 1990s during a search for potential viral causes of non-A, non-B hepatitis. Although TTVs have been found to be highly prevalent in healthy individuals, the clinical significance of this viral group remains uncertain. Currently, there are no known diseases directly attributed to TTV infection. However, studies have suggested a potential association of TTV with liver-related diseases, immune disorders, and certain cancers.
The primary concern associated with TTV is its transmission through contaminated blood products during blood transfusions and organ transplants. Despite the high prevalence of TTV in the general population, the risk of actual transmission and subsequent clinical consequences remain quite low. This is partly due to the implementation of strict screening measures in blood banks and organ donation centers.
In conclusion, Transfusion Transmitted Virus (TTV) refers to a group of small DNA viruses that are primarily transmitted through blood transfusions or organ transplants. Although their clinical significance remains uncertain, there is ongoing research to understand their potential association with various diseases. Strict screening and safety measures have significantly reduced the risk of TTV transmission during medical procedures involving blood products or organ transplantation.
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