How Do You Spell TRANSFORMYLASES?

Pronunciation: [tɹansfˈɔːmɪlˌe͡ɪsɪz] (IPA)

Transformylases is a word commonly encountered in biochemistry that refers to enzymes that add formyl groups to various molecules. The phonetic transcription of this word is /ˌtrænsfɔːrmaɪˈleɪsɪz/, and it is pronounced as trans-for-my-lay-sis. The spelling of Transformylases can be explained through the breakdown of the word. The prefix "trans-" refers to change or across, while "formyl" describes the chemical structure of a molecule. "-ases" is a suffix added to enzyme names. In combination, this word indicates an enzyme that transforms molecules by adding a formyl group.

TRANSFORMYLASES Meaning and Definition

1. Transformylases are a group of enzymes that play a crucial role in several metabolic pathways. These enzymes are responsible for catalyzing the transfer of transformyl groups from a donor molecule to an acceptor molecule. Transformyl groups are small chemical groups composed of a formyl group attached to a nitrogen atom.

   In biological systems, transformylase enzymes are primarily involved in nucleotide metabolism. They are responsible for the transfer of transformyl groups to nucleotide precursors, such as purines and pyrimidines, during their biosynthesis. This transformylation process is an essential step in the production of these nucleotides, which are vital for DNA and RNA synthesis.

   Furthermore, transformylases are also involved in the post-translational modification of certain proteins. They can add transformyl groups to specific amino acids within a protein sequence, thereby influencing protein function and activity.

   The catalytic activity of transformylases relies on the presence of cofactors and coenzymes, such as tetrahydrofolate (THF) and N10-formyltetrahydrofolate. These molecules serve as carriers of the transformyl group during the enzymatic reaction.

   The study of transformylases is of significant interest in the fields of biochemistry and pharmacology. Understanding the mechanisms of these enzymes can have important implications in cancer research and the development of drugs that target nucleotide metabolism.

Common Misspellings for TRANSFORMYLASES

• rransformylases
• fransformylases
• gransformylases
• yransformylases
• 6ransformylases
• 5ransformylases
• teansformylases
• tdansformylases
• tfansformylases
• ttansformylases
• t5ansformylases
• t4ansformylases
• trznsformylases
• trsnsformylases
• trwnsformylases
• trqnsformylases
• trabsformylases
• tramsformylases
• trajsformylases
• trahsformylases

Etymology of TRANSFORMYLASES

The word "Transformylases" has a specific etymology related to the field of biology and biochemistry.

The term "Transformylases" is derived from the words "trans" and "formylase". "Trans" comes from the Latin word "trans", meaning "across" or "beyond". "Formylase" is derived from the word "formyl", which refers to a chemical group composed of a carbon atom double-bonded to an oxygen atom and single-bonded to a hydrogen atom (H-C=O or R-C=O-H). The suffix "-ase" is typically used in biochemistry to denote an enzyme.

In this context, "Transformylases" specifically refers to a group of enzymes involved in a process called "formylation".